{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T06:27:47Z","timestamp":1783664867801,"version":"3.55.0"},"reference-count":40,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,6,23]],"date-time":"2019-06-23T00:00:00Z","timestamp":1561248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23 HL128859"],"award-info":[{"award-number":["K23 HL128859"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Antifungal prophylaxis strategies for lung transplant recipients vary without consensus or standard of care. Our current study aims to identify antifungal prophylaxis practices in the United States.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From November 29, 2018, to February 15, 2019, we emailed surveys to medical directors of adult lung transplant centers. An alternate physician representative was approached if continued non\u2010response after three survey attempts. Descriptive statistics were used to report findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010four of 62 (71.0%) eligible centers responded. All Organ Procurement and Transplantation Networks were represented. Only four (9.1%) centers used pre\u2010transplant prophylaxis for prevention of tracheobronchitis (3 of 4) and invasive fungal disease (4 of 4). Thirty\u2010nine of forty (97.5%) centers used post\u2010transplant prophylaxis: 36 (90.0%) universal and 3 (7.5%) pre\u2010emptive\/selective prophylaxis. Most centers used nebulized amphotericin with a systemic agent (26 of 36, 72.2%). Thirty\u2010two of thirty\u2010six (88.9%) centers continued universal prophylaxis beyond the hospital setting. Duration of prophylaxis ranged from the post\u2010transplant hospitalization to lifelong with most centers (25 of 36, 69.4%) discontinuing prophylaxis 6\u00a0months or less post\u2010transplant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Most United States' lung transplant centers utilize a universal prophylaxis with nebulized amphotericin and a systemic triazole for 6\u00a0months or less post\u2010transplant. Very few centers use pre\u2010transplant antifungal prophylaxis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.13630","type":"journal-article","created":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T14:54:26Z","timestamp":1559919266000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Antifungal prophylaxis in lung transplant: A survey of United States' transplant centers"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1187-5059","authenticated-orcid":false,"given":"Kelly M.","family":"Pennington","sequence":"first","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine Mayo Clinic Rochester Minnesota USA"},{"name":"Robert D. and Patricia E. Kern Center for the Science of Healthcare Delivery Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen J.","family":"Yost","sequence":"additional","affiliation":[{"name":"Robert D. and Patricia E. Kern Center for the Science of Healthcare Delivery Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricio","family":"Escalante","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymund R.","family":"Razonable","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine Mayo Clinic Rochester Minnesota USA"},{"name":"William J. von Liebig Center for Transplantation and Clinical Regeneration Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassie C.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine Mayo Clinic Rochester Minnesota USA"},{"name":"Robert D. and Patricia E. Kern Center for the Science of Healthcare Delivery Mayo Clinic Rochester Minnesota USA"},{"name":"William J. von Liebig Center for Transplantation and Clinical Regeneration Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2009.01076.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.12516"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12131"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02635.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02734.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2006.01548.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12071"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365548.2012.691207"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e318275fe69"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12187"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa061094"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12724"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2008.09.020"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2007.00209.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(01)00364-3"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2009.11.603"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200108150-00036"},{"key":"e_1_2_9_19_1","first-page":"CD004291","article-title":"Antifungal agents for preventing fungal infections in solid organ transplant recipients","volume":"3","author":"Playford EG","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-006-0182-3"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa061098"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05219-11"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2012.05.003"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciq188"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2003.09.028"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.12337"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03375.x"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1053\/srin.2002.36442"},{"key":"e_1_2_9_29_1","unstructured":"Scientific Registry of Transplant Recipient.https:\/\/www.srtr.org\/transplant-centers\/?organ=lung&recipientType=adult&query=. 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