{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:13:19Z","timestamp":1790813599680,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,7,31]],"date-time":"2019-07-31T00:00:00Z","timestamp":1564531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Many living kidney donors (LDs) are young at donation; yet there are little data on long\u2010term LD follow\u2010up. We report on 66 LDs who donated \u226550\u00a0years ago: 22 (33.3%) are still alive (current age, 78.5\u00a0\u00b1\u00a07.25\u00a0years); 39 (59%) died (mean age at death, 74.2\u00a0\u00b1\u00a012.3\u00a0years); and 5 are lost to follow\u2010up (mean age at last contact, 68.7\u00a0\u00b1\u00a04.6\u00a0years). Those who died were older at donation (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). Causes of death included 12 (30.8% of deaths) cardiovascular diseases, 9 (23.0%) respiratory failures, 5 (12.8%) malignancies and 4 (10.3%) infections, and 9 (23%) were unknown or miscellaneous. Forty\u2010nine living donors (74%) developed hypertension at a mean age of 59.9\u00a0\u00b1\u00a014.0\u00a0years; 12 (18%) developed diabetes at a mean age of 62\u00a0\u00b1\u00a019.4\u00a0years; and 11 (16.7%) developed proteinuria at a mean age of 60.6\u00a0\u00b1\u00a018.2\u00a0years\u2014each at a similar incidence as seen in the age\u2010matched general population. At last follow\u2010up, the eGFR by CKD\u2010EPI (mean\u00a0\u00b1\u00a0SD) for donors currently alive was 60.2\u00a0\u00b1\u00a013.4\u00a0mL\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup>; for those that died, 54.0\u00a0\u00b1\u00a021.5\u00a0mL\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup>; for those lost to follow\u2010up, 55.6\u00a0\u00b1\u00a07.5\u00a0mL\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup>. ESRD developed in 2 (3.3%). SF\u201036 quality of life health survey scores (n\u00a0=\u00a021) were\u00a0similar to the age\u2010matched general population.<\/jats:p>","DOI":"10.1111\/ctr.13657","type":"journal-article","created":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T14:30:11Z","timestamp":1562596211000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Kidney donor outcomes\u00a0\u2265\u00a050\u00a0years after donation"],"prefix":"10.1111","volume":"33","author":[{"given":"Daniel O.","family":"Keys","sequence":"first","affiliation":[{"name":"Division of Renal Diseases and Hypertension, Department of Medicine University of Minnesota Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Jackson","sequence":"additional","affiliation":[{"name":"Informatics Services for Researching &amp; Reporting Fairview Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Berglund","sequence":"additional","affiliation":[{"name":"Informatics Services for Researching &amp; Reporting Fairview Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9957-639X","authenticated-orcid":false,"given":"Arthur J.","family":"Matas","sequence":"additional","affiliation":[{"name":"Division of Transplantation, Department of Surgery University of Minnesota Minneapolis Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,31]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1038-5282.2001.00400.x-i1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.237"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1995.355"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2015.58"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14011"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfw429"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.7326\/M17-1235"},{"key":"e_1_2_7_9_1","volume-title":"Surgery of the Soul: Reflections on a Curious Career","author":"Murray JE","year":"2001"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0804883"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2015091018"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03816.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13173"},{"key":"e_1_2_7_14_1","unstructured":"https:\/\/optn.transplant.hrsa.gov\/. 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