{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:31:05Z","timestamp":1772843465212,"version":"3.50.1"},"reference-count":40,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T00:00:00Z","timestamp":1570147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Several studies in solid organ transplantation have shown a correlation between donor and recipient sex mismatch and risk of graft loss. In this study, we aimed to analyze the impact of donor and recipient sex matching on patient and pancreas graft survival in a large single\u2010center cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed all first simultaneous pancreas\u2010kidney transplants performed between 1979 and 2017 at the Medical University of Innsbruck.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 452 patients, 54.6% (247) received a sex\u2010matched transplant. Patient survival (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.86), death\u2010censored pancreas graft survival (dcPGS, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.26), and death\u2010censored kidney graft survival (dcKGS, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.24) were similar between the sex\u2010matched and sex\u2010mismatched groups. Patient survival and dcPGS at 1, 5, and 15\u00a0years were 95.9%, 90.0%, and 62.1% and 86.1%, 77.1%, and 56.7% in the sex\u2010matched group and 93.6%, 86.2%, and 62.4% and 83.1%, 73.3%, and 54.3% in the sex\u2010mismatched group. Sex matching led to a lower odds of severe postoperative complications (41.2% vs 49.0%; OR 0.57, 95%CI 0.33\u20100.97; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.038); however, no increased odds of other adverse postoperative outcomes was detected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study demonstrates that sex matching reduced the odds of postoperative complications but did not impact other early and late outcome parameters in our cohort.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.13717","type":"journal-article","created":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T13:58:56Z","timestamp":1569247136000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Sex matching does not impact the outcome after simultaneous pancreas\u2010kidney transplantation"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2100-6914","authenticated-orcid":false,"given":"Franka","family":"Messner","sequence":"first","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna W.","family":"Etra","sequence":"additional","affiliation":[{"name":"Department of Surgery Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5884-2604","authenticated-orcid":false,"given":"Christine E.","family":"Haugen","sequence":"additional","affiliation":[{"name":"Department of Surgery Johns Hopkins University School of Medicine Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7297-7476","authenticated-orcid":false,"given":"Claudia","family":"B\u00f6sm\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Maglione","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubert","family":"Hackl","sequence":"additional","affiliation":[{"name":"Division of Bioinformatics Medical University of Innsbruck Biocenter Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Riedmann","sequence":"additional","affiliation":[{"name":"Medical Statistics Informatics and Health Economics Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rupert","family":"Oberhuber","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benno","family":"Cardini","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Resch","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Scheidl","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raimund","family":"Margreiter","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dietmar","family":"\u00d6fner","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Schneeberger","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5450-7996","authenticated-orcid":false,"given":"Christian","family":"Margreiter","sequence":"additional","affiliation":[{"name":"Department of Visceral, Transplant and Thoracic Surgery Medical University of Innsbruck Innsbruck Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-014-3353-2"},{"key":"e_1_2_8_3_1","unstructured":"Statistical Report 2017 | Eurotransplant;2017.https:\/\/www.eurotransplant.org\/cms\/index.php?page=sr2017. Accessed March 17 2019."},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000543751.04757.43"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2016.147645"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2015.290"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60992-7"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.genm.2012.07.004"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2016.10.015"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10354-011-0895-5"},{"issue":"4","key":"e_1_2_8_11_1","first-page":"545","article-title":"Gender disparity in kidney transplantation","volume":"19","author":"Naghibi O","year":"2008","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000255583.34329.dd"},{"key":"e_1_2_8_13_1","first-page":"184","article-title":"Gender matches in liver transplant allocation: matched and mismatched male\u2010female donor\u2010recipient combinations; long\u2010term follow\u2010up of more than 2000 patients at a single center","volume":"2","author":"Schoening WN","year":"2016","journal-title":"Exp Clin Transplant"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.40"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2008.01827.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezu340"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2004.05.014"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/tri.12488"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.12649"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2009.06.098"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2004.07.046"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfm487"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2005.05.005"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12026-014-8514-3"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008101110"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep29298"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2004.00236.x"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00104-007-1362-0"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.12659\/AOT.883691"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31827381a8"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02996.x"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2014.06.045"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1900\/RDS.2011.8.6"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2012.02.005"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91797-7"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e31817352b9"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701423"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-03-344390"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.11.023"},{"key":"e_1_2_8_40_1","first-page":"148457","article-title":"H\u2010Y antigen incompatibility not associated with adverse immunologic graft outcomes: deceased donor pair analysis of the OPTN database","volume":"2011","author":"Keith DS","year":"2011","journal-title":"J Tranplantation"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.12659\/AOT.892394"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.13717","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.13717","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ctr.13717","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.13717","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T22:21:43Z","timestamp":1694211703000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.13717"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,4]]},"references-count":40,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1111\/ctr.13717"],"URL":"https:\/\/doi.org\/10.1111\/ctr.13717","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,4]]},"assertion":[{"value":"2019-07-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13717"}}