{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:30:26Z","timestamp":1753878626704,"version":"3.41.2"},"reference-count":17,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,5,25]],"date-time":"2020-05-25T00:00:00Z","timestamp":1590364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We assessed the impact of donor multiorgan procurement on survival following orthotopic heart transplantation (OHT). From the UNOS STAR database, we included all adult (\u226518\u00a0Y) heart transplants (OHT) performed since 2000 and used donor IDs to determine how many other organs were procured from the same donor as the recipient's heart allograft (regardless of recipient). The Kaplan\u2010Meier survival functions and risk\u2010adjusted Cox proportional hazards regression models were computed to assess the association of multiorgan procurement with post\u2013heart transplantation mortality. We included 40\u00a0336 OHT patients. Including the heart, the median number of donor organs procured was 3 (IQR, 3\u20104). Heart donors underwent liver procurement in 89.7%; kidney(s) in 98.1% (single 95%, bilateral 5%); lung(s) in 38.0% (single 28%, bilateral 72%); pancreas in 10.4%; and intestine in 1.6%. Following risk adjustment across 16 recipient\u2010 and donor\u2010specific variables, an increasing number of organs procured were independently associated with reduced post\u2010OHT mortality (HR 0.98, 95% CI 0.96\u20100.99, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.025). Though no significant associations were found examining specific organ types, double lung procurement trended toward a protective effect (HR 0.96, 0.92\u20101.01, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.086), with counts of non\u2010lung organs procured still bordering on significance (HR 0.97, 95% CI 0.95\u20101.00, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.067). These results likely reflect improved multiorgan donor quality.<\/jats:p>","DOI":"10.1111\/ctr.13901","type":"journal-article","created":{"date-parts":[[2020,5,13]],"date-time":"2020-05-13T10:51:23Z","timestamp":1589367083000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Multiorgan procurement is associated with a survival benefit after heart transplantation"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6895-7659","authenticated-orcid":false,"given":"Jonathan Trent","family":"Magruder","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshikazu","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Sperry","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles R.","family":"Vasquez","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8667-6591","authenticated-orcid":false,"given":"Benjamin","family":"Smood","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua C.","family":"Grimm","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavan","family":"Atluri","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Bermudez","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"Acker","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joyce W.","family":"Wald","sequence":"additional","affiliation":[{"name":"Division of Cardiology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Cantu","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisa","family":"Cevasco","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Department of Surgery University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,25]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_8_2_1","DOI":"10.1016\/j.athoracsur.2011.04.030"},{"doi-asserted-by":"publisher","key":"e_1_2_8_3_1","DOI":"10.1136\/heartjnl-2017-311435"},{"doi-asserted-by":"publisher","key":"e_1_2_8_4_1","DOI":"10.1016\/j.healun.2009.08.007"},{"doi-asserted-by":"publisher","key":"e_1_2_8_5_1","DOI":"10.1038\/sj.bmt.1704069"},{"doi-asserted-by":"publisher","key":"e_1_2_8_6_1","DOI":"10.1161\/01.CIR.0000138393.99310.1c"},{"doi-asserted-by":"publisher","key":"e_1_2_8_7_1","DOI":"10.1016\/j.healun.2017.02.002"},{"doi-asserted-by":"publisher","key":"e_1_2_8_8_1","DOI":"10.1111\/tid.12896"},{"doi-asserted-by":"publisher","key":"e_1_2_8_9_1","DOI":"10.1111\/j.1399-0012.2011.01504.x"},{"doi-asserted-by":"publisher","key":"e_1_2_8_10_1","DOI":"10.1016\/S0735-1097(19)31483-4"},{"doi-asserted-by":"publisher","key":"e_1_2_8_11_1","DOI":"10.1111\/jocs.12406"},{"doi-asserted-by":"publisher","key":"e_1_2_8_12_1","DOI":"10.1111\/ctr.13768"},{"doi-asserted-by":"publisher","key":"e_1_2_8_13_1","DOI":"10.1016\/j.exger.2018.06.019"},{"doi-asserted-by":"publisher","key":"e_1_2_8_14_1","DOI":"10.1097\/TP.0b013e3181e6f1eb"},{"doi-asserted-by":"publisher","key":"e_1_2_8_15_1","DOI":"10.1111\/ajt.13981"},{"doi-asserted-by":"publisher","key":"e_1_2_8_16_1","DOI":"10.1016\/j.healun.2019.08.001"},{"unstructured":"Multi\u2010organ transplant (MOT) nearly doubles in six years: What are the ethical implications? \u2010 UNOS.https:\/\/unos.org\/news\/in-focus\/multi-organ-transplant-nearly-doubles-in-six-years\/. Accessed February 5 2020.","key":"e_1_2_8_17_1"},{"issue":"5","key":"e_1_2_8_18_1","first-page":"555","article-title":"Multiple\u2010organ transplantation from a single donor","volume":"38","author":"Loebe M","year":"2011","journal-title":"Texas Heart Inst J"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fctr.13901","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.13901","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ctr.13901","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.13901","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T10:38:28Z","timestamp":1693910308000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.13901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,25]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1111\/ctr.13901"],"URL":"https:\/\/doi.org\/10.1111\/ctr.13901","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"type":"print","value":"0902-0063"},{"type":"electronic","value":"1399-0012"}],"subject":[],"published":{"date-parts":[[2020,5,25]]},"assertion":[{"value":"2020-04-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13901"}}