{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T03:04:35Z","timestamp":1782961475182,"version":"3.54.5"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,6,3]],"date-time":"2020-06-03T00:00:00Z","timestamp":1591142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Tertiary hyperparathyroidism is a common cause of hypercalcemia after kidney transplantation (KT) and has been associated with renal dysfunction, bone mineral density loss, and increased risk of fracture and cardiovascular events. In a previous 12\u2010month clinical trial, we demonstrated that subtotal parathyroidectomy was more effective than cinacalcet for controlling hypercalcemia. In the current study, we retrospectively evaluate whether this effect is maintained after 5\u00a0years of follow\u2010up. In total, 24 patients had data available at 5\u00a0years, 13 in the cinacalcet group and 11 in the parathyroidectomy group. At 5\u00a0years, 7 of 11 patients (64%) in the parathyroidectomy group and 6 of 13 patients (46%) in the cinacalcet group (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.44) showed normocalcemia. However, recurrence of hypercalcemia was only observed in the cinacalcet group (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.016). Subtotal parathyroidectomy retained a greater reduction in intact parathyroid hormone (iPTH) compared with cinacalcet group. No differences were observed in kidney function and incidence of fragility fractures between both groups. Cinacalcet was discontinued in 5 out of 13 patients. In conclusion, in kidney transplant patients with tertiary hyperparathyroidism recurrence of hypercalcemia after 5\u2010year follow\u2010up is more frequent in cinacalcet than after subtotal parathyroidectomy.<\/jats:p>","DOI":"10.1111\/ctr.13988","type":"journal-article","created":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T23:37:46Z","timestamp":1590104266000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Long\u2010term results of a randomized study comparing parathyroidectomy with cinacalcet for treating tertiary hyperparathyroidism"],"prefix":"10.1111","volume":"34","author":[{"given":"Pablo","family":"Moreno","sequence":"first","affiliation":[{"name":"Department of Surgery Hospital Universitari de Bellvitge University of Barcelona L\u2019Hospitalet de Llobregat Barcelona 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Bellvitge (IDIBELL) L\u2019Hospitalet de Llobregat Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Francos","sequence":"additional","affiliation":[{"name":"Department of Surgery Hospital Universitari de Bellvitge University of Barcelona L\u2019Hospitalet de Llobregat Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergi","family":"Codina","sequence":"additional","affiliation":[{"name":"Nephrology Department Hospital Universitari de Bellvitge University of Barcelona Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL) L\u2019Hospitalet de Llobregat Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Manonelles","sequence":"additional","affiliation":[{"name":"Nephrology Department Hospital Universitari de Bellvitge University of Barcelona Institut d\u2019Investigaci\u00f3 Biom\u00e8dica de Bellvitge (IDIBELL) L\u2019Hospitalet de Llobregat 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