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Kidney transplant recipients are commonly prescribed renin\u2010angiotensin\u2010aldosterone system (AAS) inhibitors given the prevalence of hypertension, diabetes, and cardiovascular disease. As the angiotensin\u2010converting enzyme 2 (ACE2) facilitates the entry of coronaviruses into target cells, there have been hypotheses that preexisting use of renin\u2010angiotensin\u2010aldosterone system (RAAS) inhibitors may increase the risk of developing severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) infection. Given the common use of RAAS inhibitors among solid organ transplant recipients, we sought to review the RAAS cascade, the mechanism of SARS\u2010CoV\u20102 entry, and pertinent data related to the effect of RAAS inhibitors on ACE2 to guide management of solid organ transplant recipients during the COVID\u201019 pandemic. At present, there is no clear evidence to support the discontinuation of RAAS inhibitors in solid organ transplant recipients during the COVID\u201019 pandemic.<\/jats:p>","DOI":"10.1111\/ctr.13991","type":"journal-article","created":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T21:16:15Z","timestamp":1590268575000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["What solid organ transplant healthcare providers should know about renin\u2010angiotensin\u2010aldosterone system inhibitors and COVID\u201019"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4872-6500","authenticated-orcid":false,"given":"Sunnie Y.","family":"Wong","sequence":"first","affiliation":[{"name":"Division of Abdominal Transplantation Dept. of Surgery Stanford University  Stanford CA 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