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Associations of opioid and NSAID prescription fills with baseline factors were examined by logistic regression (adjusted odds ratio, <jats:sub>LCL<\/jats:sub>aOR<jats:sub>UCL<\/jats:sub>). Among 23,565 donors, opioid prescriptions were highest during days 0\u201014 (36.6%), but 12.6% of donors filled opioids during days 183\u2010365. NSAID prescriptions rose from 0.5% during days 0\u201014 to 3.3% during days 183\u2010365. Women filled opioids more commonly than men, and black donors filled both opioids and NSAIDs more commonly than white donors. After covariate adjustment, significant correlates of opioid prescription fills during days 183\u2010365 included obesity (aOR,<jats:sub>1.24<\/jats:sub>1.38<jats:sub>1.53<\/jats:sub>), less than college education (aOR,<jats:sub>1.19<\/jats:sub>1.31<jats:sub>1.43<\/jats:sub>), smoking (aOR,<jats:sub>1.33<\/jats:sub>1.45<jats:sub>1.58<\/jats:sub>), and nephrectomy complications (aOR,<jats:sub>1.11<\/jats:sub>1.29<jats:sub>1.49<\/jats:sub>). NSAID prescription fills in year 1 were not associated with differences in estimated glomerular filtration rate, incidence of proteinuria or new\u2010onset hypertension at the first and second year postdonation. Prescription fills for opioids and NSAIDs for LKDs varied with demographic and clinic traits. Future work should examine longer\u2010term outcome implications to help inform safe analgesic regimen choices after donation.<\/jats:p>","DOI":"10.1111\/ctr.14000","type":"journal-article","created":{"date-parts":[[2020,6,5]],"date-time":"2020-06-05T19:55:59Z","timestamp":1591386959000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prescription patterns of opioids and non\u2010steroidal anti\u2010inflammatory drugs in the first year after living kidney donation: An analysis of U.S. Registry and Pharmacy fill records"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6470-2472","authenticated-orcid":false,"given":"Luke S.","family":"Vest","sequence":"first","affiliation":[{"name":"Center for Abdominal Transplantation Saint Louis University School of Medicine St. Louis MO 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of Iowa School of Medicine Iowa City IA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8182-1238","authenticated-orcid":false,"given":"Chi Yuan","family":"Hsu","sequence":"additional","affiliation":[{"name":"Nephrology Department of Medicine UCSF San Francisco CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit X.","family":"Garg","sequence":"additional","affiliation":[{"name":"Nephrology Department of Medicine Western University London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorry L.","family":"Segev","sequence":"additional","affiliation":[{"name":"Center for Transplantation Johns Hopkins School of Medicine Baltimore MD USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan B.","family":"Massie","sequence":"additional","affiliation":[{"name":"Center for Transplantation Johns Hopkins School of Medicine Baltimore MD 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