{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T05:27:23Z","timestamp":1774330043682,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,7,15]],"date-time":"2020-07-15T00:00:00Z","timestamp":1594771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Backgrounds<\/jats:title><jats:p>We evaluate whether it is safe to accept donors with Gilbert's syndrome (GS) for a living donor liver transplantation (LDLT) or not. This study is the first controlled study to be conducted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between January 2004 and May 2014, 600 LDLTs which used right lobe liver grafts were performed in our center. Forty\u2010five of the 600 donors had a GS diagnosis. For a control group, 99 donors without GS who had completed 1\u00a0year or more of follow\u2010up were selected retrospectively and consecutively. The clinical results of the donors and recipients were then analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 45 donors with GS and 99 donors without GS were included. There were no significant differences in patient demographics, actual graft weight, remnant ratio, portal and ductal variations, pre\u2010peri\u2010post\u2013operative liver enzymes. The donors with GS had significantly higher bilirubin levels compared with the control group at first reading, at maximal peak, and post\u2010operative 1\u20107\u00a0days, 1st and 6th months (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001 for all readings). Post\u2010operative complication ratio was 40% in GS, 34.3% in non\u2010GS group. In GS and non\u2010GS group, hospitalization period was 10.2 and 9.2\u00a0days, respectively. The 1\u2010year donor survival rate was 100% for both groups and 1\u2010year recipient survival was similar who have donors with GS and non\u2010GS (93.3%; 92.9%, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.93).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of right lobe grafts from donors with GS appears to be safe for donor health.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14015","type":"journal-article","created":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T12:02:38Z","timestamp":1593000158000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Adult living donor liver transplantation from donors with Gilbert\u2019s syndrome: Is it safe?"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2080-7528","authenticated-orcid":false,"given":"Murat","family":"Akyildiz","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Koc University, School of Medicine Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8199-6617","authenticated-orcid":false,"given":"Gokhan","family":"Gungor","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Selcuk Un\u0131versity, School of Medicine Konya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5956-7461","authenticated-orcid":false,"given":"Necdet","family":"Guler","sequence":"additional","affiliation":[{"name":"General Surgery and Liver Transplantation Center Yeditepe University Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8086-0956","authenticated-orcid":false,"given":"Sencan","family":"Acar","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Sakarya University Hospital, School of Medicine Sakarya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4159-893X","authenticated-orcid":false,"given":"Yalcin","family":"Erdogan","sequence":"additional","affiliation":[{"name":"Liver Transplantation Center Sisli Florence Nightingale Hospital Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5856-5384","authenticated-orcid":false,"given":"Genco","family":"Gencdal","sequence":"additional","affiliation":[{"name":"Liver Transplantation Center Atasehir Memorial Hospital Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1240-7233","authenticated-orcid":false,"given":"Murat","family":"Dayanga\u00e7","sequence":"additional","affiliation":[{"name":"Liver Transplantation Center Sisli Florence Nightingale Hospital Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9899-1521","authenticated-orcid":false,"given":"Yaman","family":"Tokat","sequence":"additional","affiliation":[{"name":"Liver Transplantation Center Sisli Florence Nightingale Hospital Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12907"},{"key":"e_1_2_7_3_1","first-page":"303","volume-title":"Sleisenger and Foltran\u2019s Gastrointestinal and Liver Disease","author":"Feldman 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