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In this single\u2010center study, we compared post\u2010heart transplant (OHT, orthotopic heart transplantation) survival for AL and ATTR amyloidosis, hypothesizing that these differences would persist post\u2010OHT. Thirty\u2010nine patients with CA (AL, n\u00a0=\u00a018; ATTR, n\u00a0=\u00a021) and 1023 non\u2010amyloidosis subjects undergoing OHT were included. Cox proportional hazards modeling was used to evaluate the impact of amyloid subtype and era (early era: from 2001 to 2007; late era: from 2008 to 2018) on survival post\u2010OHT. Survival for non\u2010amyloid patients was greater than ATTR (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.034) and AL (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001) patients in the early era. One, 3\u2010, and 5\u2010year survival rates were higher for ATTR patients than AL patients in the early era (100% vs 75%, 67% vs 50%, and 67% vs 33%, respectively, for ATTR and AL patients). Survival in the non\u2010amyloid cohort was 87% at 1 year, 81% at 3 years, and 76% at 5 years post\u2010OHT. In the late era, AL and ATTR patients had unadjusted 1\u2010year, 3\u2010year, and 5\u2010year survival rates of 100%, which was comparable to non\u2010amyloid patients (90% vs 84% vs 81%). Overall, these findings demonstrate that in the current era, differences in post\u2010OHT survival for AL compared to ATTR are diminishing; OHT outcomes for selected patients with CA do not differ from non\u2010amyloidosis patients.<\/jats:p>","DOI":"10.1111\/ctr.14028","type":"journal-article","created":{"date-parts":[[2020,7,5]],"date-time":"2020-07-05T14:58:20Z","timestamp":1593961100000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Outcomes after heart transplantation for al compared to ATTR cardiac amyloidosis"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1729-7464","authenticated-orcid":false,"given":"Jan M.","family":"Griffin","sequence":"first","affiliation":[{"name":"Center for Advanced Cardiac Care Division of Cardiology Columbia College of Physicians &amp; Surgeons New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Chiu","sequence":"additional","affiliation":[{"name":"Center for Advanced Cardiac Care Division of Cardiology Columbia College of Physicians &amp; 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