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No difference was found among 30\u2010day mortality (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.11) and postoperative complications between groups. Both unadjusted and adjusted survival was significantly higher for group <jats:italic>young\u2010R\/young\u2010D<\/jats:italic> than that of other groups, in which survival was similar [adjusted HR for mortality of 2.0(1.2\u20103.4), 2.1(1.4\u20103.8) and 2.5(1.6\u20104.1) for groups <jats:italic>old\u2010R\/young\u2010D, young\u2010R\/old\u2010D, old\u2010R\/old\u2010D,<\/jats:italic> respectively]. Compared to other groups, the incidence of grade\u00a0\u2265\u00a02 CAV was significantly lower in <jats:italic>old\u2010R\/young\u2010D<\/jats:italic> group [adjusted HR 0.4(0.2\u20100.7)]. Among young recipients, the rate of acute grade\u00a0\u2265\u00a02 rejection episodes was higher in those receiving an old donor graft (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.04). Old recipient groups were more affected by neoplasms and severe renal failure than young recipient groups (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.01). Employment of hearts from donors \u226550\u00a0years of age adversely affects survival in recipients &lt;60\u00a0years of age but does not influence outcomes in older recipients. Also, donor and recipient ages seem to have opposite effects on incidence of rejections and CAV of high grade.<\/jats:p>","DOI":"10.1111\/ctr.14043","type":"journal-article","created":{"date-parts":[[2020,7,12]],"date-time":"2020-07-12T12:36:55Z","timestamp":1594557415000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Donor\u2010recipient age interaction and the impact on clinical results after heart transplantation"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5825-1561","authenticated-orcid":false,"given":"Andrea","family":"Lechiancole","sequence":"first","affiliation":[{"name":"Cardiothoracic Department University Hospital of Udine Udine Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Vendramin","sequence":"additional","affiliation":[{"name":"Cardiothoracic Department University Hospital of Udine Udine 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