{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T13:31:13Z","timestamp":1779888673744,"version":"3.53.1"},"reference-count":21,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,9,27]],"date-time":"2020-09-27T00:00:00Z","timestamp":1601164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Elderly patients are the fastest growing population requiring renal replacement therapy. As previous studies have shown a survival benefit of kidney transplantation compared to dialysis for end\u2010stage renal disease, we sought to evaluate if this survival benefit extends to octogenarians.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single\u2010center retrospective cohort study of renal allograft recipients \u226580\u00a0years transplanted from 1999 to 2014 who were compared to patients listed during the same period that did not proceed to transplantation. A secondary matched group was selected from the UNOS transplant waitlist database. The primary outcome was patient survival. Secondary outcomes included graft survival and rejection incidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010three transplanted patients were compared to 71 patients waitlisted at our center and 66 patients from the UNOS database. Patients in the study group were transplanted 20.8\u00a0\u00b1\u00a016.1\u00a0months after listing. Patient survival was 87.8% at 6\u00a0months and 1\u00a0year and 71.4% at 3\u00a0years. Kidney transplantation was associated with a significant decrease in the risk of death after listing (HR: 0.22, CI: 0.11\u20100.45, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>With escalating life expectancy, kidney transplantation is a suitable treatment option in eligible octogenarians.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14074","type":"journal-article","created":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T20:14:14Z","timestamp":1599164054000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Survival benefit of renal transplantation in octogenarians"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2232-8894","authenticated-orcid":false,"given":"Bharath R.","family":"Ravichandran","sequence":"first","affiliation":[{"name":"Department of Pharmacy University of Maryland Medical Center Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8305-7296","authenticated-orcid":false,"given":"Tracy M.","family":"Sparkes","sequence":"additional","affiliation":[{"name":"Department of Pharmacy University of Maryland Medical Center Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1841-5135","authenticated-orcid":false,"given":"Brian M.","family":"Masters","sequence":"additional","affiliation":[{"name":"Department of Pharmacy University of Maryland Medical Center Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beje","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Nephrology University of Maryland School of Medicine Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moses","family":"Demehin","sequence":"additional","affiliation":[{"name":"Department of Pharmacy University of Maryland Medical Center Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan S.","family":"Bromberg","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Maryland School of Medicine Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdolreza","family":"Haririan","sequence":"additional","affiliation":[{"name":"Department of Nephrology University of Maryland School of Medicine Baltimore MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,27]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"2018 USRDS annual data report: Epidemiology of Kidney Disease in the United States","author":"United States Renal Data System","year":"2018"},{"key":"e_1_2_6_3_1","unstructured":"RobertsAW OgunwoleSU BlakesleeL RabeMA.The Population 65 Years and Older in the United States: 2016. 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