{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:38:10Z","timestamp":1783654690828,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T00:00:00Z","timestamp":1601251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The incidence of recurrent laryngeal nerve injury (RLNI) after heart transplantation has not been well studied. This can manifest as vocal cord dysfunction causing dysphonia. Previous research is limited to aortic, coronary bypass, and valvular surgery. Identifying RLNI after heart transplantation is important in order to more accurately detail complications associated with this major surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective study assessing 972 adult patients who underwent orthotopic heart transplantation between 2010\u20102019. Primary outcome was incidence of RLNI. Secondary outcomes were 1\u2010year mortality and length of stay. Cardiology and otolaryngology notes were examined. Key word searches were used to identify possible RLNI in patients' health care record.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>2.9% (29\/972) of patients developed new RLNI confirmed by laryngoscopy during hospitalization. Patients with RLNI had a significantly increased risk of 1\u2010year mortality (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.015) and length of stay (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.006) compared to those without RLNI. 68.9% (20\/29) of RLNI was left\u2010sided (68.9%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Recurrent laryngeal nerve injury is a recognizable adverse outcome following heart transplantation. This study supports that RLNI is associated with increased 1\u2010year mortality and length of stay. Early otolaryngology evaluation may be warranted to evaluate vocal cord mobility and address potential management.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14075","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T16:33:00Z","timestamp":1601310780000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Uniqueness of laryngeal nerve injury following heart transplantation"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5331-2620","authenticated-orcid":false,"given":"Angelo","family":"de la Rosa","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Cedars\u2010Sinai Medical Center  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Aguilar","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Cedars\u2010Sinai Medical Center  Los Angeles CA 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