{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T02:11:33Z","timestamp":1776910293304,"version":"3.51.2"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T00:00:00Z","timestamp":1603843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["AG AG036778"],"award-info":[{"award-number":["AG AG036778"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The new heart transplantation (HT) allocation policy was introduced on 10\/18\/2018. Using the UNOS registry, we examined early outcomes following HT for restrictive cardiomyopathy, hypertrophic cardiomyopathy, cardiac sarcoidosis, or cardiac amyloidosis compared to the old system. Those listed who had an event (transplant, death, or waitlist removal) prior to 10\/17\/2018 were in Era 1, and those listed on or after 10\/18\/2018 were in Era 2. The primary endpoint was death on the waitlist or delisting due to clinical deterioration. A total of 1232 HT candidates were included, 855 (69.4%) in Era 1 and 377 (30.6%) in Era 2. In Era 2, there was a significant increase in the use of temporary mechanical circulatory support and a reduction in the primary endpoint, (20.9 events per 100 PY (Era 1) vs. 18.6 events per 100 PY (Era 2), OR 1.98, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.005). Median waitlist time decreased (91 vs. 58\u00a0days, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001), and transplantation rate increased (119.0 to 204.7 transplants\/100 PY for Era 1 vs Era 2). Under the new policy, there has been a decrease in waitlist time and waitlist mortality\/delisting due to clinical deterioration, and an increase in transplantation rates for patients with infiltrative, hypertrophic, and restrictive cardiomyopathies without any effect on post\u2010transplant 6\u2010month survival.<\/jats:p>","DOI":"10.1111\/ctr.14109","type":"journal-article","created":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T19:15:08Z","timestamp":1602616508000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Comparing outcomes for infiltrative and restrictive cardiomyopathies under the new heart transplant allocation system"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1729-7464","authenticated-orcid":false,"given":"Jan M.","family":"Griffin","sequence":"first","affiliation":[{"name":"Milstein Division of Cardiology Department of Medicine Columbia University Vagelos College of Physicians and Surgeons New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ersilia M.","family":"DeFilippis","sequence":"additional","affiliation":[{"name":"Milstein Division of Cardiology Department of Medicine Columbia University Vagelos College of Physicians and Surgeons New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah","family":"Rosenblum","sequence":"additional","affiliation":[{"name":"Milstein Division of Cardiology Department of Medicine Columbia University Vagelos College of Physicians and Surgeons New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veli K.","family":"Topkara","sequence":"additional","affiliation":[{"name":"Milstein Division of Cardiology Department of Medicine Columbia University Vagelos College of Physicians and Surgeons New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin A.","family":"Fried","sequence":"additional","affiliation":[{"name":"Milstein Division of Cardiology Department of Medicine Columbia University Vagelos College of Physicians and Surgeons New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nir","family":"Uriel","sequence":"additional","affiliation":[{"name":"Milstein Division of Cardiology Department of Medicine Columbia University Vagelos College of Physicians and Surgeons New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Takeda","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Surgery Department of Surgery Columbia University Vagelos College of Physicians &amp; Surgeons New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryjane A.","family":"Farr","sequence":"additional","affiliation":[{"name":"Milstein Division of Cardiology Department of Medicine Columbia University Vagelos College of Physicians and Surgeons New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathew S.","family":"Maurer","sequence":"additional","affiliation":[{"name":"Milstein Division of Cardiology Department of Medicine Columbia University Vagelos College of Physicians and Surgeons New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8351-9219","authenticated-orcid":false,"given":"Kevin J.","family":"Clerkin","sequence":"additional","affiliation":[{"name":"Milstein Division of Cardiology Department of Medicine Columbia University Vagelos College of Physicians and Surgeons New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,28]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Organ procurement and transplantation network: policy 6: allocation of hearts and hearts\u2010lungs.2018.http:\/\/optn.transplant.hrsa.gov\/media\/1200\/optn_policies.pdf#nameddest=Policy_06"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2012.04258.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.117.004665"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.117.004378"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2013.01.987"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.114.001435"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2013.09.004"},{"key":"e_1_2_10_9_1","unstructured":"Thoracic Organ Transplant Committee.Review Board Guidance for Hypertrophic\/Restrictive (HCM\/RCM) Cardiomyopathy Exception Requests.2018.https:\/\/optn.transplant.hrsa.gov\/media\/2637\/thoracic_guidance_review_board_hcm_rcm_201806.pdf. Accessed May 26th 2020."},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2018.02.009"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2016.03.010"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2017.07.049"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.110.959288"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2019.04.011"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.12166"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2012.09.013"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16010"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2019.11.002"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.01.066"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2017.11.015"},{"issue":"6","key":"e_1_2_10_21_1","first-page":"461","article-title":"Outcomes in patients with cardiac amyloidosis undergoing heart transplantation","volume":"8","author":"Barrett C","year":"2020","journal-title":"J Am Coll Cardiol HF"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13025"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.14028"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019004369"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2007.05.006"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2013.02.116"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.109.922872"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(03)00225-0"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.14109","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ctr.14109","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.14109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T19:38:50Z","timestamp":1693597130000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.14109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,28]]},"references-count":27,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1111\/ctr.14109"],"URL":"https:\/\/doi.org\/10.1111\/ctr.14109","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,28]]},"assertion":[{"value":"2020-08-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14109"}}