{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T17:52:37Z","timestamp":1779299557710,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T00:00:00Z","timestamp":1607731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Anti\u2010glomerular basement membrane (GBM) disease causes rapidly progressive glomerulonephritis and end\u2010stage kidney disease (ESKD). Studies of post\u2010transplant outcomes in patients with ESKD due to anti\u2010GBM disease in the United States are lacking. To better characterize outcomes of transplant recipients with a history of anti\u2010GBM disease, we examined patient survival and graft survival among recipients with anti\u2010GBM disease compared with IgA nephropathy at a single center in the United States. We analyzed patient survival, graft survival, disease recurrence, and malignancy rates for kidney transplant recipients with ESKD due to biopsy\u2010proven anti\u2010GBM disease who underwent kidney transplantation at our center between 1994 and 2015. 26 patients with biopsy\u2010proven anti\u2010GBM disease and 314 patients with IgAN underwent kidney transplantation from 1994 to 2015. The incidence of graft loss was 6.2 per 100 person\u2010years for anti\u2010GBM disease, which was similar to IgAN (4.08 per 100 person\u2010years, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.09). Patient mortality for anti\u2010GBM was 0.03 per 100 person\u2010years, similar to IgAN (0.02 per 100 person\u2010years, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.12). Disease recurrence occurred in one of the 26 anti\u2010GBM patients. Four out of 26 patients (15%) developed malignancy, most commonly skin cancer. Long\u2010term graft and patient survival for patients with ESKD due to anti\u2010GBM was similar to IgAN after kidney transplantation.<\/jats:p>","DOI":"10.1111\/ctr.14179","type":"journal-article","created":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T23:39:19Z","timestamp":1606865959000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Long\u2010term outcomes in kidney transplant recipients with end\u2010stage kidney disease due to anti\u2010glomerular basement membrane disease"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8855-3421","authenticated-orcid":false,"given":"Tripti","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Medicine University of Wisconsin Hospital &amp; Clinics Madison Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talar B.","family":"Kharadjian","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Wisconsin Hospital &amp; Clinics Madison Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad C.","family":"Astor","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Wisconsin Hospital &amp; Clinics Madison Madison WI USA"},{"name":"Department of Population Health Sciences University of Wisconsin\u2010Madison School of Medicine and Public Health Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah E.","family":"Panzer","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Wisconsin Hospital &amp; Clinics Madison Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-134-11-200106050-00009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2015.04.003"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(87)80086-0"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)06077-9"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1996.495"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.13591215"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1973.14"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(81)90007-6"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1976.86"},{"issue":"2","key":"e_1_2_7_11_1","first-page":"124","article-title":"Recurrence of anti\u2010GBM antibody disease twelve years after transplantation associated with de novo IgA nephropathy","volume":"49","author":"Trpkov K","year":"1998","journal-title":"Clin Nephrol"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfg393"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2008.00912.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.1998.v32.pm9708621"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2004.09.029"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-018-1197-6"},{"issue":"3","key":"e_1_2_7_17_1","first-page":"570","article-title":"Renal transplantation for uncommon diseases. Scientific Advisory Board of the ERA\u2010EDTA Registry. 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