{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T23:48:01Z","timestamp":1781740081360,"version":"3.54.5"},"reference-count":45,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T00:00:00Z","timestamp":1609200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Obesity adversely affects wait\u2010listing and precludes patients with concomitant end\u2010stage renal disease and type 1 diabetes mellitus from getting a simultaneous pancreas and kidney transplantation (SPK).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To analyze safety and efficacy of laparoscopic sleeve gastrectomy (LSG) before SPK in severely obese type I diabetics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We assessed weight curve, complications, and graft function of three patients who underwent LSG before SPK.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>LSG was uneventful in all patients. Body mass index dropped from 38.4 (range 35.7 \u2010 39.9) before LSG to 28.5 (26.8 \u2010 30.9) until SPK, with a mean loss of 25.8% (22.4 \u2010 32.3). Interval between LSG and SPK was 364.3 (173 \u2010 587) days. Pancreas and kidney graft function was excellent, with 100% insulin\u2010free and dialysis\u2010free survival over a mean follow\u2010up of 3.6 (2.9 \u2010 4.5) years. A1C dropped from 7% (6.3 \u2010 8.2) before LSG to 4.9% (4.7 \u2010 5.3) and 4.8% (4.5 \u2010 5.1) 1 and 2\u00a0years after SPK, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LSG before SPK is safe and effective to enable severely obese type I diabetics to receive a lifesaving transplant. This is the first study analyzing the role of bariatric surgery before simultaneous pancreas and kidney transplantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14197","type":"journal-article","created":{"date-parts":[[2020,12,19]],"date-time":"2020-12-19T19:45:25Z","timestamp":1608407125000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Sleeve gastrectomy enables simultaneous pancreas and kidney transplantation in severely obese recipients"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2968-347X","authenticated-orcid":false,"given":"Fabian","family":"R\u00f6ssler","sequence":"first","affiliation":[{"name":"Department of Surgery and Transplantation University Hospital Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"H\u00fcbel","sequence":"additional","affiliation":[{"name":"Department of Nephrology University 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