{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T18:02:46Z","timestamp":1760551366572,"version":"3.41.2"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T00:00:00Z","timestamp":1614211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We investigate whether marijuana use in living kidney donor candidates is associated with psychosocial risk factors that place donors at higher risk for adverse outcomes and the unique associations between marijuana use and donor candidacy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records of 757 living kidney donor candidates were reviewed. Patients were grouped into marijuana users\/abstainers; demographic, psychiatric, and substance use variables were compared. Multivariate logistic regression assessed the independent association of marijuana use on committee approval for donation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Marijuana use was associated with lack of health insurance, legal history, lower education level, active and history of substance use disorder, active psychiatric disorder, history of multiple psychiatric diagnoses, and history of suicidality. Marijuana users were also more likely to be young, male, unmarried, and less likely to be approved for donation by the multidisciplinary selection committee. This latter association persisted in multivariate models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This is the first study to show that marijuana use is associated with psychosocial factors that could impact behavioral adherence following kidney donation, while reducing chances of committee approval for kidney donation. Special attention to potential overlay between psychosocial risk factors and marijuana use should be considered when evaluating kidney donors, particularly in context of increasingly legal use.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14248","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T16:35:44Z","timestamp":1612802144000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The relationship between marijuana use and psychosocial variables in living kidney donor candidates"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7284-6342","authenticated-orcid":false,"given":"Marci M.","family":"Loiselle","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Division of Behavioral Medicine Duke University Medical Center Durham NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaina","family":"Gulin","sequence":"additional","affiliation":[{"name":"Department of Surgery University of North Carolina Chapel Hill NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7687-7173","authenticated-orcid":false,"given":"Terra","family":"Rose","sequence":"additional","affiliation":[{"name":"Department of Allied Health Sciences and Department of Psychiatry University of North Carolina Chapel Hill NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8045-7507","authenticated-orcid":false,"given":"Eileen","family":"Burker","sequence":"additional","affiliation":[{"name":"Department of Allied Health Sciences and Department of Psychiatry University of North Carolina Chapel Hill NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8638-3852","authenticated-orcid":false,"given":"Lauren","family":"Bolger","sequence":"additional","affiliation":[{"name":"Department of Surgery University of North Carolina Chapel Hill NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6374-0298","authenticated-orcid":false,"given":"Patrick","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Division of Behavioral Medicine Duke University Medical Center Durham NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,2,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15672"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01751.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000136654.85459.1E"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000157343.27949.9F"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.22.2919"},{"key":"e_1_2_9_7_1","first-page":"15198","article-title":"Requirements for approval and re\u2010approval of transplant centers to perform organ transplants","volume":"72","author":"United States Department of Health and Human Services CfMaMS","year":"2007","journal-title":"Fed Reg"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2017.10.018"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.22.2919"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/152692480901900206"},{"volume-title":"Guidance for the Development of Program\u2010Specific Living Kidney Donation Medical Evaluation Protocols","year":"2006","author":"Organ Procurement and Transplantation Network","key":"e_1_2_9_11_1"},{"key":"e_1_2_9_12_1","unstructured":"Organ Procurement and Transplantation Network.OPTN Policy 14: Living Donation;2020.https:\/\/optn.transplant.hrsa.gov\/media\/1200\/optn_policies.pdf. 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