{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T20:10:33Z","timestamp":1788898233617,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,4,19]],"date-time":"2021-04-19T00:00:00Z","timestamp":1618790400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cardiac amyloidosis (CA) has been historically noted with poor outcomes after heart transplant (HTx). However, strict patient selection, appropriate multi\u2010organ transplant, and aggressive post\u2010transplant therapy can result in favorable outcomes. We present the experience in the largest single\u2010center cohort of CA patients post\u2010HTx in the recent era.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between January 2010 and December 2018, 51 CA patients underwent HTx\u201413 light\u2010chain amyloidosis (AL) and 38 transthyretin amyloidosis (ATTR), 49 were included. Endpoints included 3\u2010year survival, freedom from cardiac allograft vasculopathy (CAV), and freedom from non\u2010fatal major adverse cardiac events (NF\u2010MACE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall 3\u2010year survival was 81.6% (69.2% for AL and 86% for ATTR) and was comparable to survival for patients transplanted for non\u2010amyloid restrictive cardiomyopathy (RCM) in the same period (89%, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.46). Three\u2010year freedom from CAV (84% vs. 89%, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.98), NF\u2010MACE (82% vs. 83%, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.96), and any\u2010treated rejection (95% vs. 89%, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.54) were also comparable in both groups. No recurrence in amyloid was noted in endomyocardial biopsies. Six patients (46%) with AL amyloidosis underwent autologous stem cell transplant 1\u2010year post\u2010HTx, and two patients (8%) with variant ATTR\u2010CA underwent combined heart\u2010liver transplant due to cardiac cirrhosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In the current era, both AL and ATTR cardiac amyloidosis patients have acceptable outcomes after heart transplantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14308","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T07:38:03Z","timestamp":1617781083000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Intermediate\u2010term outcomes of heart transplantation for cardiac amyloidosis in the current era"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8296-7343","authenticated-orcid":false,"given":"Gaurang 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