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As patients with CF are living longer, extra\u2010pulmonary manifestations may develop including pancreatic failure, which manifests as exocrine insufficiency, and CF\u2010related diabetes (CFRD). Both of these can be managed through pancreas transplantation. Pancreas transplantation is usually performed in combination with another organ, most often with a kidney transplant for end\u2010stage diabetic nephropathy. In the CF patient population, the two settings where inclusion of a pancreas transplant should be considered would be in combination with a lung transplant for CF pulmonary disease, or in combination with a liver for CF\u2010related liver disease with cirrhosis. This report will discuss this topic in detail, including a review of the literature regarding combinations of lung\/pancreas and liver\/pancreas transplant.<\/jats:p>","DOI":"10.1111\/ctr.14371","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T11:57:11Z","timestamp":1621943831000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Pancreas transplantation for cystic fibrosis: A frequently missed opportunity"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8708-1506","authenticated-orcid":false,"given":"Jonathan A.","family":"Fridell","sequence":"first","affiliation":[{"name":"Department of Surgery Division of Abdominal Transplant Surgery Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3644-5381","authenticated-orcid":false,"given":"Molly A.","family":"Bozic","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology Riley Hospital for Children Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2729-1798","authenticated-orcid":false,"given":"Benjamin J.","family":"Ulrich","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Abdominal Transplant Surgery Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Lutz","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Abdominal Transplant Surgery Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Powelson","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Abdominal Transplant Surgery Indiana University School of Medicine Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,6,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra043184"},{"key":"e_1_2_10_3_1","unstructured":"Cystic Fibrosis Foundation. 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