{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:18:44Z","timestamp":1788405524987,"version":"build-2803163510"},"reference-count":43,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T00:00:00Z","timestamp":1637020800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Delayed graft function (DGF) after kidney transplantation is a common occurrence and correlates with poor graft and patient outcomes. Donor characteristics and care are known to impact DGF. We attempted to show the relationship between achievement of specific donor management goals (DMG) and DGF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective case\u2010control study using data from 14\u00a0046 adult kidney donations after brain death from hospitals in 18 organ procurement organizations (OPOs) which were transplanted to adult recipients between 2012 and 2018. Data on DMG compliance and donor, recipient, and ischemia\u2010related factors were used to create multivariable logistic regression models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall rate of DGF was 29.4%. Meeting DMGs for urine output and vasopressor use were associated with decreased risk of DGF. Sensitivity analyses performed with different imputation methods, omitting recipient factors, and analyzing multiple time points yielded largely consistent results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The development of DMGs continues to show promise in improving outcomes in the kidney transplant recipient population. Studies have already shown increased kidney utilization in smaller cohorts, as well as other organs, and shown decreased rates of DGF. Additional research and analysis are required to assess interactions between meeting DMGs and correlation versus causality in DMGs and DGF.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14528","type":"journal-article","created":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T17:49:27Z","timestamp":1636134567000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Organ donor management goals and delayed graft function in adult kidney transplant recipients"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7148-970X","authenticated-orcid":false,"given":"Rishi","family":"Kothari","sequence":"first","affiliation":[{"name":"Department of Anesthesia and Perioperative Care University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Tolles","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Harbor\u2010University of California Los Angeles Medical Center  Los Angeles California USA"},{"name":"David Geffen School of Medicine at the University of California Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7645-3530","authenticated-orcid":false,"given":"Dieter","family":"Adelmann","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Perioperative Care University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger J.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Harbor\u2010University of California Los Angeles Medical Center  Los Angeles California USA"},{"name":"David Geffen School of Medicine at the University of California Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren J.","family":"Malinoski","sequence":"additional","affiliation":[{"name":"Department of Surgery Division of Trauma Critical Care and Acute Care Surgery Oregon Health &amp; Science University  Portland Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus U.","family":"Niemann","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Perioperative Care University of California San Francisco  San Francisco California USA"},{"name":"Department of Surgery University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2016.07.001"},{"key":"e_1_2_9_3_1","unstructured":"National Data \u2010 OPTN. Accessed March 19 2020.https:\/\/optn.transplant.hrsa.gov\/data\/view\u2010data\u2010reports\/national\u2010data\/"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3182855544"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.12090"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2000.00235.x"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2010.03179.x"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.3.s4.11.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199704150-00011"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfl042"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2011.01232.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2010.10.006"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2014.188"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000093254.31868.85"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2482-13-22"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2018.08.011"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1310"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00331.x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(96)80014-6"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.7182\/prtr.1.6.4.e1g711321k55563r"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15127"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0802289"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000958"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.2002.20810.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.045131"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e31822779e5"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2017.06.014"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2020.05.025"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2016.12.004"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2014.967"},{"key":"e_1_2_9_31_1","first-page":"e13571","article-title":"Deceased organ donor factors influencing pancreatic graft transplantation and survival","volume":"0","author":"Sally MB","journal-title":"Clin Transplant"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0000000000000638"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TA.0000168708.78049.32"},{"key":"e_1_2_9_34_1","unstructured":"FranklinGA SantosAP SmithJW GalbraithS HarbrechtBG GarrisonRN Optimization of donor management goals yields increased organ use. Published: June2010. Accessed: February 5 2020.https:\/\/www.ingentaconnect.com\/content\/sesc\/tas\/2010\/00000076\/00000006\/art00021#"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/152692480901900307"},{"key":"e_1_2_9_36_1","unstructured":"Not Human Subjects Research | UCSF Institutional Review Board. Accessed: March 20 2020.https:\/\/irb.ucsf.edu\/not-human-subjects-research#procedures"},{"key":"e_1_2_9_37_1","unstructured":"Data request instructions \u2010 OPTN. Accessed: January 16 2020.https:\/\/optn.transplant.hrsa.gov\/data\/request-data\/data-request-instructions\/"},{"key":"e_1_2_9_38_1","unstructured":"Organ Procurement and Transplantation Network.A Guide to Calculating and Interpreting the Kidney Donor Profle Index (KDPI). Published online: May 15 2019. Accessed: January 16 2020.https:\/\/optn.transplant.hrsa.gov\/media\/1512\/guide_to_calculating_interpreting_kdpi.pdf"},{"key":"e_1_2_9_39_1","unstructured":"SRTR Posttransplant Outcomes. Accessed January 16 2020.https:\/\/www.srtr.org\/reports\u2010tools\/posttransplant\u2010outcomes\/"},{"key":"e_1_2_9_40_1","unstructured":"vanBuurenS Groothuis\u2010OudshoornK&VinkG et al.Mice: Multivariate Imputation by Chained Equations; 2019. Accessed: January 16 2020.https:\/\/CRAN.R\u2010project.org\/package=mice"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000002688"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-200211150-00014"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181ac620b"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1177\/2054358118791148"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.14528","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ctr.14528","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.14528","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T09:32:55Z","timestamp":1693215175000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.14528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,16]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1111\/ctr.14528"],"URL":"https:\/\/doi.org\/10.1111\/ctr.14528","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,16]]},"assertion":[{"value":"2021-05-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e14528"}}