{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T17:57:20Z","timestamp":1771005440622,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T00:00:00Z","timestamp":1638144000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hypertrophic cardiomyopathy (HCM) presents with a hypertrophied left ventricle (LV). It is often associated with LV outflow tract obstruction (LVOTO) and a risk for sudden death. This study aimed to describe outcomes of patients with HCM who underwent liver transplant (LT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective review was conducted for patients diagnosed with HCM undergoing LT. Patient characteristics, preoperative echocardiography results, HCM risk of sudden cardiac death prediction model score, and 5\u2010year mortality were examined. A univariable Cox proportional hazards model was used to evaluate the association between risk factors and 5\u2010year mortality. All tests were two\u2010sided with the alpha level set at .05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010nine patients were included in the analysis. Six patients (21%) had a perioperative cardiopulmonary complication. The 5\u2010year survival rate was 61% (95% CI, 45\u201382). The analyzed risk factors showed that 5\u2010year post\u2010LT survival was significantly predicted by maximal LV outflow tract gradient at rest\u00a0&gt;\u00a060\u00a0mmHg (hazard ratio, 1.04 [95% CI, 1.01\u20101.06]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Preoperative LV outflow tract resting gradient\u00a0&gt;\u00a060\u00a0mmHg was associated with 5\u2010year post\u2010LT mortality. The results suggest the severity of LVOTO identified by echocardiography is a prognostic tool for patients with HCM after LT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14538","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T13:00:12Z","timestamp":1637154012000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Preoperative echocardiography as a prognostic tool for liver transplant in patients with hypertrophic cardiomyopathy"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4446-3993","authenticated-orcid":false,"given":"Sher\u2010Lu","family":"Pai","sequence":"first","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan M.","family":"Chadha","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilana I.","family":"Logvinov","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2175-4819","authenticated-orcid":false,"given":"Tara J.","family":"Brigham","sequence":"additional","affiliation":[{"name":"Mayo Medical Library Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kymberly D.","family":"Watt","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Rochester Minnesota USA"},{"name":"Mayo Clinic William J. von Liebig Center for Transplantation and Clinical Regeneration Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuo","family":"Li","sequence":"additional","affiliation":[{"name":"Biostatistics Unit Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3614-6939","authenticated-orcid":false,"given":"William C.","family":"Palmer","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph L.","family":"Blackshear","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9571-234X","authenticated-orcid":false,"given":"Stephen","family":"Aniskevich","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Perioperative Medicine 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