{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T12:48:45Z","timestamp":1792759725126,"version":"4.5.0"},"reference-count":42,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,1,7]],"date-time":"2022-01-07T00:00:00Z","timestamp":1641513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The association between pre\u2010transplant dialysis duration and post\u2010transplant outcomes may vary by the population and endpoints studied. We conducted a population\u2010based cohort study using linked healthcare databases from Ontario, Canada including kidney transplant recipients (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a04461) from 2004 to 2014. Our primary outcome was total graft failure (i.e., death, return to dialysis, or pre\u2010emptive re\u2010transplant). Secondary outcomes included death\u2010censored graft failure, death with graft function, mortality, hospitalization for cardiovascular events, hospitalization for infection, and hospital readmission. We presented results by pre\u2010transplant dialysis duration (pre\u2010emptive transplant, and .01\u20131.43, 1.44\u20132.64, 2.65\u20134.25, 4.26\u20136.45, and 6.46\u201336.5 years, for quintiles 1\u20135). After adjusting for clinical characteristics, pre\u2010emptive transplantation was associated with a lower rate of total graft failure (adjusted hazard ratio [aHR] .68, 95% CI: .46, .99), while quintile 4 was associated with a higher rate (aHR 1.31, 95% CI: 1.01, 1.71), when compared to quintile 1. There was no significant relationship between dialysis duration and death\u2010censored graft failure, cardiovascular events, or hospital readmission. For death with graft function and mortality, quintiles 3\u20135 had a significantly higher aHR compared to quintile 1, while for infection, quintiles 2\u20135 had a higher aHR. Longer time on dialysis was associated with an increased rate of several adverse post\u2010transplant outcomes.\n                  <\/jats:p>","DOI":"10.1111\/ctr.14553","type":"journal-article","created":{"date-parts":[[2021,12,12]],"date-time":"2021-12-12T05:54:15Z","timestamp":1639288455000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Pre\u2010transplant maintenance dialysis duration and outcomes after kidney transplantation: A multicenter population\u2010based cohort study"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5304-8038","authenticated-orcid":false,"given":"Kyla L.","family":"Naylor","sequence":"first","affiliation":[{"name":"ICES  Ontario Canada"},{"name":"Department of Epidemiology and Biostatistics Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5021-9831","authenticated-orcid":false,"given":"S. Joseph","family":"Kim","sequence":"additional","affiliation":[{"name":"ICES  Ontario Canada"},{"name":"Division of Nephrology University Health Network University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Paul","family":"Kuwornu","sequence":"additional","affiliation":[{"name":"ICES  Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie N.","family":"Dixon","sequence":"additional","affiliation":[{"name":"ICES  Ontario Canada"},{"name":"Department of Epidemiology and Biostatistics Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit X.","family":"Garg","sequence":"additional","affiliation":[{"name":"ICES  Ontario Canada"},{"name":"Department of Epidemiology and Biostatistics Western University  London Ontario Canada"},{"name":"Division of Nephrology Western University  London Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan K.","family":"McCallum","sequence":"additional","affiliation":[{"name":"ICES  Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory A.","family":"Knoll","sequence":"additional","affiliation":[{"name":"Department of Medicine (Nephrology) University of Ottawa and the Ottawa Hospital Research Institute  Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000003136"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfy099"},{"key":"e_1_2_10_4_1","unstructured":"British Transplantation Society. Guidelines for living donor kidney transplantation.2018. 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