{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:20:20Z","timestamp":1753878020110,"version":"3.41.2"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T00:00:00Z","timestamp":1646352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Most transplant centers do not screen kidney donor candidates for sickle cell trait (SCT) and many decline candidates with SCT since it may associate with kidney disease. We compared 17 kidney donors with SCT to propensity score matched donor controls on mortality, reduced eGFR, proteinuria and kidney failure. The prevalence of SCT in African American (AA) donors was 11 per 1000 compared to 73 per 1000 in non\u2010donor AA. Donors with SCT were younger; 33 versus 35 years in controls, nine were AA, six were White, and two were listed as other or unknown ethnicities. After a follow\u2010up period of 18.2 \u00b1 10.5 years, the proportions of donors with SCT and controls who were alive, developed hypertension or cardiovascular disease were similar. No donor with SCT developed an eGFR &lt;30 mL\/min\/1.73\u00a0m<jats:sup>2<\/jats:sup> or kidney failure. SCT was, however, associated with increased risk of proteinuria; RR 5.71 (95% CI 5.7 \u2013 22.7), <jats:italic>P<\/jats:italic> = .01. This small and preliminary case series suggest that donors with SCT should perhaps be considered more often provided they were aware of the lack of evidence to support liberal acceptance and that these outcomes reported here likely represent a healthy cohort of donors with SCT.<\/jats:p>","DOI":"10.1111\/ctr.14626","type":"journal-article","created":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T11:09:20Z","timestamp":1645873760000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcomes of kidney donors with sickle cell trait: A preliminary analysis"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6126-1544","authenticated-orcid":false,"given":"Sean A.","family":"Hebert","sequence":"first","affiliation":[{"name":"Department of Medicine Houston Methodist Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6630-2157","authenticated-orcid":false,"given":"Nisarg V.","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Department of Medicine Houston Methodist Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3810-8557","authenticated-orcid":false,"given":"Sanad","family":"Al\u2010Amin","sequence":"additional","affiliation":[{"name":"Department of Medicine Houston Methodist Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6500-2072","authenticated-orcid":false,"given":"Angelina R.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Department of Medicine Houston Methodist Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1217-8941","authenticated-orcid":false,"given":"Dina N.","family":"Murad","sequence":"additional","affiliation":[{"name":"Department of Medicine Houston Methodist Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5059-4404","authenticated-orcid":false,"given":"Duc T.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Medicine Houston Methodist Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1024-5813","authenticated-orcid":false,"given":"Edward A.","family":"Graviss","sequence":"additional","affiliation":[{"name":"Department of Pathology and Genomic Medicine Institute for Academic Medicine Houston Methodist Research Institute  Houston Texas USA"},{"name":"Department of Surgery Houston Methodist Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1567-9592","authenticated-orcid":false,"given":"Hassan N.","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Medicine Houston Methodist Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.09.003"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2016101086"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1310345"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(12)70055-5"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2007.00611.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.01932.x"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2019050502"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001770"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2012.04321.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-9-200905050-00006"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.3697"},{"volume-title":"Stata Reference Manual: Release 16","year":"2019","author":"Lasso StataCorp. 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