{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:30:24Z","timestamp":1753878624690,"version":"3.41.2"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T00:00:00Z","timestamp":1671667200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Organ dysfunction (OD) after lung transplantation can reflect preoperative organ failure, intraoperative acute organ damage and post\u2010operative complications. We assessed two OD scoring systems, both the PEdiatric Logistic Organ Dysfunction (PELOD) and the pediatric Sequential Organ Failure Assessment (pSOFA) scores, in recognizing risk factors for morbidity as well as recipients with prolonged post\u2010transplant morbidity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Medical records of recipients from January 2009 to March 2016 were reviewed. PELOD and pSOFA scores were calculated on post\u2010transplant days 1\u20103. Risk factors assessed included cystic fibrosis (CF), prolonged surgical time and worst primary graft dysfunction (PGD) score amongst others. Patients were classified into three groups based on their initial scores (group A) and subsequent trends either uptrending (group B) or downtrending (group C). Morbidity outcomes were compared between these groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Total 98 patients were enrolled aged 0\u201320 years. Risk factors for higher pSOFA scores \u2265 5 on day 1 included non\u2010CF diagnosis and worst PGD scores (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.0006 and <jats:italic>p<\/jats:italic>\u00a0=\u00a0.03, respectively). Kruskal Wallis analysis comparing pSOFA group A versus B versus C scores showed significantly prolonged ventilatory days (median 1\u00a0vs. 4\u00a0vs. 2, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.0028) and ICU days (median 4\u00a0vs. 10\u00a0vs. 6, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.007). Similarly, PELOD group A versus B versus C scores showed significantly prolonged ventilatory days (1\u00a0vs. 5\u00a0vs. 2, <jats:italic>p<\/jats:italic>\u00a0=\u00a0&lt;\u00a0.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Implementing pSOFA scores bedside is a more effective tool compared to PELOD in identifying risk factors for worsened OD post\u2010lung transplant and can be valuable in providing direction on morbidity outcomes in the ICU.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14863","type":"journal-article","created":{"date-parts":[[2022,12,8]],"date-time":"2022-12-08T19:10:17Z","timestamp":1670526617000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Application of organ dysfunction assessment scores following pediatric lung transplantation"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1124-1611","authenticated-orcid":false,"given":"Chinyere","family":"O'Connor","sequence":"first","affiliation":[{"name":"McGovern Medical School UT Health Science Center at Houston  Houston Texas USA"},{"name":"Department of Pediatrics Texas Children's Hospital  Houston Texas USA"},{"name":"Division of Pediatric Critical Care Texas Children's Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flor M.","family":"Munoz","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Texas Children's Hospital  Houston Texas USA"},{"name":"Baylor College of Medicine Texas Children's Hospital  Houston Texas USA"},{"name":"Section of Infectious Diseases and Transplant Texas Children's Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria C.","family":"Gazzaneo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Texas Children's Hospital  Houston Texas USA"},{"name":"Division of Pediatric Critical Care Texas Children's Hospital  Houston Texas USA"},{"name":"Baylor College of Medicine Texas Children's Hospital  Houston Texas USA"},{"name":"Section of Pulmonary Medicine and Lung Transplant Texas Children's Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernestina","family":"Melicoff","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Texas Children's Hospital  Houston Texas USA"},{"name":"Baylor College of Medicine Texas Children's Hospital  Houston Texas USA"},{"name":"Section of Pulmonary Medicine and Lung Transplant Texas Children's Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shailendra","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Texas Children's Hospital  Houston Texas USA"},{"name":"Baylor College of Medicine Texas Children's Hospital  Houston Texas USA"},{"name":"Section of Pulmonary Medicine and Lung Transplant Texas Children's Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fong","family":"Lam","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Texas Children's Hospital  Houston Texas USA"},{"name":"Division of Pediatric Critical Care Texas Children's Hospital  Houston Texas USA"},{"name":"Baylor College of Medicine Texas Children's Hospital  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge A.","family":"Coss\u2010Bu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Texas Children's Hospital  Houston Texas USA"},{"name":"Division of Pediatric Critical Care Texas Children's Hospital  Houston Texas USA"},{"name":"Baylor College of Medicine Texas Children's Hospital  Houston Texas 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