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Research in organ transplantation has historically focused on reducing the incidence and impact of rejection on allograft survival and minimizing or eliminating the need for chronic immunosuppressive therapies. There has been less emphasis and investment in therapies to improve patient\u2010reported outcomes including health\u2010related quality of life and side\u2010effects. Patient\u2010focused drug development (PFDD) is a new and important emphasis of the Food and Drug Administration (FDA) that provides a guiding philosophy for incorporating the patient experience into drug development and evaluation. The American Society of Transplantation (AST) Board of Directors commissioned this working group to prepare for the conduct of a comprehensive patient survey assessing unmet immunosuppressive therapy needs. This paper aims to describe the basis for why it is important to conduct this survey and briefly outline the plan for broad stakeholder engagement to ensure the information gained is diverse, inclusive, and relevant for advancing PFDD in organ transplant recipients.<\/jats:p>","DOI":"10.1111\/ctr.14876","type":"journal-article","created":{"date-parts":[[2022,12,5]],"date-time":"2022-12-05T08:24:34Z","timestamp":1670228674000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A viewpoint describing the American Society of Transplantation rationale to conduct a comprehensive patient survey assessing unmet immunosuppressive therapy needs"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7273-4589","authenticated-orcid":false,"given":"David J.","family":"Taber","sequence":"first","affiliation":[{"name":"Department of Surgery Medical University of South Carolina  Charleston South Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0969-1998","authenticated-orcid":false,"given":"Elisa J.","family":"Gordon","sequence":"additional","affiliation":[{"name":"Department of Surgery Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0847-0368","authenticated-orcid":false,"given":"Michelle T.","family":"Jesse","sequence":"additional","affiliation":[{"name":"Henry Ford Transplant Institute Internal Medicine, Henry Ford Health  Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7268-1517","authenticated-orcid":false,"given":"Larissa","family":"Myaskovsky","sequence":"additional","affiliation":[{"name":"Center for Healthcare Equity in Kidney Disease and Department of Internal Medicine University of New Mexico Health Sciences Center  Albuquerque New Mexico USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5762-7881","authenticated-orcid":false,"given":"John Devin","family":"Peipert","sequence":"additional","affiliation":[{"name":"Department of Medical Social Sciences &amp; Northwestern University Transplant Outcomes Research Collaboration Northwestern University Feinberg School of Medicine  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8973-9538","authenticated-orcid":false,"given":"Allison","family":"Jaure","sequence":"additional","affiliation":[{"name":"Sydney School of Public Health The University of Sydney, Camperdown  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3853-967X","authenticated-orcid":false,"given":"Roshan","family":"George","sequence":"additional","affiliation":[{"name":"Emory University and Children's Healthcare of Atlanta  Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6189-5499","authenticated-orcid":false,"given":"William","family":"Fitzsimmons","sequence":"additional","affiliation":[{"name":"Colleges of Pharmacy and Medicine University of Illinois at Chicago  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"for the American Society of Transplantation Board of Directors","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,13]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16463"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc-2020-001962"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03686.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-2277.2008.00674.x"},{"key":"e_1_2_5_6_1","unstructured":"USRDS.Annual Data Report: End Stage Renal Disease in the United States.2018."},{"key":"e_1_2_5_7_1","unstructured":"Exploring the state of the science of solid organ transplantation and disability. 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