{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T15:01:00Z","timestamp":1780585260741,"version":"3.54.1"},"reference-count":65,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T00:00:00Z","timestamp":1672185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Long\u2010term outcomes of kidney transplantation from deceased donors (DDKTs) with terminal acute kidney injury (AKI) are not well defined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Single center retrospective review of DDKTs from 1\/31\/07\u201012\/31\/19. AKI kidneys were defined by a doubling of the donor's admission serum creatinine (SCr) level AND a terminal SCr \u22652.0\u00a0mg\/dl.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 188 AKI DDKTs were performed, including 154 from brain\u2010dead standard criteria donors (SCD). Mean donor age was 36 years and mean Kidney Donor Profile Index was 50%; mean admission and terminal SCr levels were 1.3 and 3.1\u00a0mg\/dl, respectively. With a mean follow\u2010up of 94 months (median 89 months), overall patient (both 71.3%) and graft survival (54% AKI vs. 57% non\u2010AKI) rates were comparable to concurrent DDKTs from brain\u2010dead non\u2010AKI SCDs (<jats:italic>n<\/jats:italic>\u00a0=\u00a0769). Delayed graft function (DGF) was higher in AKI kidney recipients (47%\u00a0vs. 20% non\u2010AKI DDKTs,<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.0001). DGF was associated with lower graft survival in recipients of both AKI and non\u2010AKI SCD kidneys but the impact was earlier and more pronounced in non\u2010AKI recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Despite having more than twice the incidence of DGF, kidneys from deceased donors with terminal AKI have long\u2010term outcomes comparable to non\u2010AKI SCD kidneys and represent a safe and effective method to expand the donor pool.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14886","type":"journal-article","created":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T07:44:26Z","timestamp":1671176666000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Long\u2010term outcomes of kidney transplantation from deceased donors with terminal acute kidney injury: Single center experience and literature 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