{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T06:29:45Z","timestamp":1775888985733,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T00:00:00Z","timestamp":1680220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Many kidney transplant (KT) centers decline patients with a body mass index (BMI) \u226540\u00a0kg\/m<jats:sup>2<\/jats:sup>. This study's aim was to evaluate KT outcomes according to recipient BMI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a single\u2010center, retrospective review of adult KTs comparing BMI \u226540 patients (<jats:italic>n<\/jats:italic>\u00a0=\u00a084, BMI\u00a0=\u00a042\u00a0\u00b1\u00a02\u00a0kg\/m<jats:sup>2<\/jats:sup>) to a matched BMI\u00a0&lt;\u00a040 cohort (<jats:italic>n<\/jats:italic>\u00a0=\u00a084, BMI\u00a0=\u00a028\u00a0\u00b1\u00a05\u00a0kg\/m<jats:sup>2<\/jats:sup>). Patients were matched for age, gender, race, diabetes, and donor type.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>BMI \u226540 patients were on dialysis longer (5.2\u00a0\u00b1\u00a03.2\u00a0years vs. 4.1\u00a0\u00b1\u00a03.5\u00a0years, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.03) and received lower kidney donor profile index (KDPI) kidneys (40\u00a0\u00b1\u00a025%\u00a0vs. 53\u00a0\u00b1\u00a026%, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.003). There were no significant differences in prevalence of delayed graft function, reoperations, readmissions, wound complications, patient survival, or renal function at 1\u00a0year. Long\u2010term graft survival was higher for BMI \u226540 patients, including after adjusting for KDPI (BMI \u226540: aHR\u00a0=\u00a01.79, 95% CI\u00a0=\u00a01.09\u20132.9). BMI \u226540 patients had similar BMI change in the first year post\u2010transplant (delta BMI: BMI\u00a0\u2265\u00a040 +.9\u00a0\u00b1\u00a03.3 vs. BMI\u00a0&lt;\u00a040 +1.1\u00a0\u00b1\u00a03.2, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.59).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Overall outcomes after KT were comparable in BMI \u226540 patients compared to a matched cohort with lower BMI with improved long\u2010term graft survival in obese patients. BMI\u2010based exclusion criteria for KT should be reexamined in favor of a more individualized approach.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.14903","type":"journal-article","created":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T16:44:50Z","timestamp":1672764290000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparable kidney transplant outcomes in selected patients with a body mass index\u00a0\u2265\u00a040: A personalized medicine approach to recipient selection"],"prefix":"10.1111","volume":"37","author":[{"given":"Marie L.","family":"Jacobs","sequence":"first","affiliation":[{"name":"University of Rochester School of Medicine  Rochester New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karanpreet","family":"Dhaliwal","sequence":"additional","affiliation":[{"name":"University of Washington Medical Center  Seattle Washington 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C.","family":"Farney","sequence":"additional","affiliation":[{"name":"Department of Surgery Section of Transplantation Atrium Health Wake Forest Baptist  Winston Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6460-7974","authenticated-orcid":false,"given":"Giuseppe","family":"Orlando","sequence":"additional","affiliation":[{"name":"Department of Surgery Section of Transplantation Atrium Health Wake Forest Baptist  Winston Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amber","family":"Reeves\u2010Daniel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Section of Nephrology Atrium Health Wake Forest Baptist  Winston Salem North Carolina 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