{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T13:51:16Z","timestamp":1783691476529,"version":"3.55.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T00:00:00Z","timestamp":1698969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The Living Kidney Donor Profile Index (LKDPI) was developed in the United States to predict graft outcomes based on donor characteristics. However, there are significant differences in donor demographics, access to transplantation, proportion of ABO incompatibility, and posttransplant mortality in Asian countries compared with the United States.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We evaluated the clinical relevance of the LKDPI score in a Korean kidney transplant cohort by analyzing 1860 patients who underwent kidney transplantation between 2000 and 2019. Patients were divided into three groups according to LKDPI score: &lt;0, 1\u201319.9, and \u226520.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During a median follow\u2010up of 119\u00a0months, 232 recipients (12.5%) experienced death\u2010censored graft loss, and 98 recipients (5.3%) died. High LKDPI scores were significantly associated with increased risk of death\u2010censored graft loss independent of recipient characteristics (LKDPI 1\u201319.9: HR 1.389, 95% CI 1.036\u20131.863; LKDPI \u226520: HR 2.121, 95% CI 1.50\u20132.998). High LKDPI score was also significantly associated with increased risk of biopsy\u2010proven acute rejection and impaired graft renal function. By contrast, overall patient survival rates were comparable among the LKDPI groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>High LKDPI scores were associated with an increased risk of death\u2010censored graft loss, biopsy\u2010proven acute rejection, and impaired graft renal function among a Korean kidney transplant cohort.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.15178","type":"journal-article","created":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T17:11:57Z","timestamp":1699031517000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical relevance of the living kidney donor profile index in Korean kidney transplant recipients"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6033-5094","authenticated-orcid":false,"given":"Hyun Jeong","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Surgery Yonsei University 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Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6305-452X","authenticated-orcid":false,"given":"Hyung Woo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5378-7797","authenticated-orcid":false,"given":"Jaeseok","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5732-2583","authenticated-orcid":false,"given":"Beom Seok","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul Republic of Korea"},{"name":"The Research Institute for Transplantation Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1364-6989","authenticated-orcid":false,"given":"Kyu Ha","family":"Huh","sequence":"additional","affiliation":[{"name":"Department of Surgery Yonsei University College of Medicine  Seoul Republic of Korea"},{"name":"The Research Institute for Transplantation Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8975-8381","authenticated-orcid":false,"given":"Myoug Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery Yonsei University College of Medicine  Seoul Republic of Korea"},{"name":"The Research Institute for Transplantation Yonsei University College of Medicine  Seoul Republic of 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