{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T05:37:37Z","timestamp":1781415457869,"version":"3.54.1"},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Post\u2010transplant diabetes mellitus (PTDM) is associated with an increased risk of post\u2010transplant cardiovascular diseases, and several risk factors of PTDM have been shown in the literature. Yet, the relationship between hepatic and pancreatic steatosis with post\u2010transplant diabetes mellitus remains vague. We aimed to evaluate pancreatic steatosis, a novel component of metabolic syndrome, and hepatic steatosis association with post\u2010transplant diabetes mellitus in a single\u2010center retrospective cohort study conducted on kidney transplant recipients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We have performed a single\u2010center retrospective cohort study involving all kidney transplant recipients. We have utilized pretransplant Fibrosis\u20104, nonalcoholic fatty liver disease fibrosis score, and abdominal computed tomography for the assessment of visceral steatosis status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We have included 373 kidney transplant recipients with a mean follow\u2010up period of 32 months in our final analysis. Post\u2010transplant diabetes mellitus risk is associated with older age (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001), higher body\u2010mass index (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001), nonalcoholic fatty liver disease\u2010fibrosis score (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.002), hepatic (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001) or pancreatic (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001) steatosis on imaging and higher pre\u2010transplant serum triglyceride (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.003) and glucose levels (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.001) after multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study illustrates that recipients\u2019 pancreatic steatosis is an independent predictive factor for post\u2010transplant diabetes mellitus including in kidney transplant patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.15204","type":"journal-article","created":{"date-parts":[[2023,12,2]],"date-time":"2023-12-02T17:03:33Z","timestamp":1701536613000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Pancreatic steatosis is an independent risk factor for post\u2010transplant diabetes mellitus in kidney transplant patients"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2229-5140","authenticated-orcid":false,"given":"Nuri Baris","family":"Hasbal","sequence":"first","affiliation":[{"name":"Division of Nephrology Department of Medicine Koc University School of Medicine  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidar","family":"Copur","sequence":"additional","affiliation":[{"name":"Department of Medicine Koc University School of Medicine  Istanbul 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