{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:29:32Z","timestamp":1753878572565,"version":"3.41.2"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T00:00:00Z","timestamp":1705968000000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K23DK133729"],"award-info":[{"award-number":["K23DK133729"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Incidental kidneys cysts are typically considered benign, but the presence of cysts is more frequent in individuals with other early markers of kidney disease. We studied the association of donor kidney cysts with donor and recipient outcomes after living donor kidney transplantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospective identified 860 living donor transplants at our center (1\/1\/2011\u20137\/31\/2022) without missing data. Donor cysts were identified by review of pre\u2010donation CT scan reports. We used linear regression to study the association between donor cysts and 6\u2010month single\u2010kidney estimated glomerular filtration rate (eGFR) increase, and time\u2010to\u2010event analyses to study the association between donor cysts and recipient death\u2010censored graft failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among donors, 77% donors had no kidney cysts, 13% had \u22651 cyst on the kidney not donated, and 11% only had cysts on the donated kidney. In adjusted linear regression, cysts on the donated kidney and kidney not donated were not significantly associated with 6\u2010month single\u2010kidney eGFR increase. Among transplants, 17% used a transplanted kidney with a cyst and 6% were from donors with cysts only on the kidney not transplanted. There was no association between donor cyst group and post\u2010transplant death\u2010censored graft survival. Results were similar in sensitivity analyses comparing transplants using kidneys with no cysts versus 1\u20132 cysts versus \u22653 cysts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Kidney cysts in living kidney donors were not associated with donor kidney recovery or recipient allograft longevity, suggesting incidental kidney cysts need not be taken into account when determining living donor candidate suitability or the laterality of planned donor nephrectomy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.15242","type":"journal-article","created":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T04:55:00Z","timestamp":1706072100000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between donor kidney cysts and donor and recipient outcomes after living donor kidney transplantation"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3563-6124","authenticated-orcid":false,"given":"Brendan R.","family":"Emmons","sequence":"first","affiliation":[{"name":"Department of Medicine Division of Nephrology Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"},{"name":"Columbia University Renal Epidemiology Group  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel T.","family":"Adler","sequence":"additional","affiliation":[{"name":"Department of Surgery and Perioperative Care Dell Medical School University of Texas at Austin  Austin Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Rodrigo","family":"Sandoval","sequence":"additional","affiliation":[{"name":"Department of Surgery Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen L.","family":"King","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Nephrology Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"},{"name":"Columbia University Renal Epidemiology Group  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5491-0278","authenticated-orcid":false,"given":"Miko","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Nephrology Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"},{"name":"Columbia University Renal Epidemiology Group  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C.","family":"Cron","sequence":"additional","affiliation":[{"name":"Department of Surgery Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5305-9685","authenticated-orcid":false,"given":"Sumit","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Nephrology Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"},{"name":"Columbia University Renal Epidemiology Group  New York New York USA"},{"name":"Department of Epidemiology Mailman School of Public Health Columbia University  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lloyd E.","family":"Ratner","sequence":"additional","affiliation":[{"name":"Department of Surgery Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1823-0117","authenticated-orcid":false,"given":"Syed Ali","family":"Husain","sequence":"additional","affiliation":[{"name":"Department of Medicine Division of Nephrology Columbia University Vagelos College of Physicians &amp; Surgeons  New York New York USA"},{"name":"Columbia University Renal Epidemiology Group  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.01.007"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.07641009"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-022-03421-8"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65373-6"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.07.075"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008040441"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2011.12.022"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/ctr.13905"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000453078"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.07150717"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2009.09.077"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2022.01.034"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2023.04.028"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2015.08.004"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-152-9-201005040-00006"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.15.14357"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2017.10.005"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000009361"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-016-4631-9"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2176-z"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2312031025"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.15242","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T08:37:24Z","timestamp":1741768644000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.15242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/ctr.15242"],"URL":"https:\/\/doi.org\/10.1111\/ctr.15242","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"type":"print","value":"0902-0063"},{"type":"electronic","value":"1399-0012"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2023-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e15242"}}