{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:39Z","timestamp":1787014059800,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T00:00:00Z","timestamp":1709683200000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    COVID\u201019 is a heterogenous infection\u2014asymptomatic to fatal. While the course of pediatric COVID\u201019 infections is usually mild or even asymptomatic, individuals after adult heart transplantation are at high risk of a severe infection. We conducted a retrospective, multicenter survey of 16 pediatric heart transplant centers in Germany, Austria and Switzerland to evaluate the risk of a severe COVID\u201019 infection after pediatric heart transplantation between 02\/2020 and 06\/2021. Twenty\u2010six subjects (11 male) with a median age of 9.77 years at time of transplantation and a median of 4.65 years after transplantation suffered from COVID\u201019 infection. The median age at time of COVID\u201010 infection was 17.20 years. Fourteen subjects had an asymptomatic COVID\u201019 infection. The most frequent symptoms were myalgia\/fatigue (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a06), cough (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a05), rhinitis (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a05), and loss of taste (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a05). Only one subject showed dyspnea. Eleven individuals needed therapy in an outpatient setting, four subjects were hospitalized. One person needed oxygen supply, none of the subjects needed non\u2010invasive or invasive mechanical ventilation. No specific signs for graft dysfunction were found by non\u2010invasive testing. In pediatric heart transplant subjects, COVID\u201019 infection was mostly asymptomatic or mild. There were no SARS\u2010CoV\u20102 associated myocardial dysfunction in heart transplant individuals.\n                  <\/jats:p>","DOI":"10.1111\/ctr.15272","type":"journal-article","created":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T05:08:26Z","timestamp":1709701706000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["COVID\u201019 infection in patients with history of pediatric heart transplant in Germany, Austria, and Switzerland"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6513-1739","authenticated-orcid":false,"given":"Sarah","family":"Ulrich","sequence":"first","affiliation":[{"name":"Department for Pediatric Cardiology and Intensive Care Medicine Ludwig\u2010Maximilians\u2010University Munich  Munchen 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