{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:28:06Z","timestamp":1753878486671,"version":"3.41.2"},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T00:00:00Z","timestamp":1711670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 59\u2010year\u2010old woman, with dilated ischemic cardiomyopathy, was urgently admitted to our Intensive Care Unit for cardiogenic shock. ECMO VA was implanted and placed on the national emergency waitlist for transplantation. A potential donation was identified ten days later. The donor was a 58\u2010year\u2010old woman, with no cardiovascular risk factors, had died of a rupture of a cerebral aneurysm with left ventricle dysfunction due to Takotsubo syndrome. Brain injuries such as hemorrhage, trauma and stroke have been extensively documented in literature to cause a surge in stress hormones, such as catecholamines. Such a surge can have a direct effect on the heart, resulting in a transient myocardial dysfunction commonly referred to as \u201cTakotsubo cardiomyopathy\u201d or \u201cbroken heart syndrome\u201d.<\/jats:p><jats:p>Many studies have shown that hearts that are dysfunctional at the start of transplant screening, with normal contractile function at the time of organ retrieval, have similar outcomes to hearts that do not have dysfunction. In our case, the transplanted heart, at the time of sampling, still had moderate dysfunction (EF 40%) which completely disappeared after the transplant.<\/jats:p>","DOI":"10.1111\/ctr.15303","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T14:23:16Z","timestamp":1711722196000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Can a \u201cbroken heart\u201d successfully be transplanted? A brief report"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9583-1581","authenticated-orcid":false,"given":"Lorenzo","family":"Giovannico","sequence":"first","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Fischetti","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Mazzone","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Parigino","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Savino","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Santeramo","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline Maria","family":"Silva","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"di Bari","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tommaso","family":"Acquaviva","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Fiore","sequence":"additional","affiliation":[{"name":"Intensive Care Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo Domenico","family":"Milano","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomaso","family":"Bottio","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit Department of Precision and Regenerative\u00a0Medicine and Ionian Area (DiMePRe\u2010J) University of Bari Medical School  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,3,29]]},"reference":[{"key":"e_1_2_1_4_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11092665"},{"key":"e_1_2_1_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(00)00193-5"},{"key":"e_1_2_1_4_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.027121"},{"key":"e_1_2_1_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.07.728"},{"key":"e_1_2_1_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2017.02.001"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.15303","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T11:09:40Z","timestamp":1713784180000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.15303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,29]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1111\/ctr.15303"],"URL":"https:\/\/doi.org\/10.1111\/ctr.15303","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"type":"print","value":"0902-0063"},{"type":"electronic","value":"1399-0012"}],"subject":[],"published":{"date-parts":[[2024,3,29]]},"assertion":[{"value":"2023-11-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e15303"}}