{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T20:31:04Z","timestamp":1770496264098,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T00:00:00Z","timestamp":1724284800000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Donation after circulatory death (DCD) donors are becoming an important source of organs for heart\u2010transplantation (HT), but there are limited data regarding their use in multiorgan\u2010HT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between January 2020 and June 2023, we identified 87 adult multiorgan\u2010HTs performed using DCD\u2010donors [77 heart\u2013kidney, 6 heart\u2013lung, 4 heart\u2013liver] and 1494 multiorgan\u2010HTs using donation after brain death (DBD) donors (1141 heart\u2013kidney, 165 heart\u2013lung, 188 heart\u2013liver) in UNOS. For heart\u2013kidney transplantations (the most common multiorgan\u2010HT combination from DCD\u2010donors), we also compared donor\/recipient characteristics, and early outcomes, including 6\u2010month mortality using Kaplan\u2013Meier (KM) and Cox hazards\u2010ratio (Cox\u2010HR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Use of DCD\u2010donors for multiorgan\u2010HTs in the United States increased from 1% in January to June 2020 to 12% in January\u2013June 2023 (<jats:italic>p<\/jats:italic> &lt; 0.001); but there was a wide variation across UNOS regions and center volumes. Compared to recipients of DBD heart\u2013kidney transplantations, recipients of DCD heart\u2013kidney transplantations were less likely to be of UNOS Status 1\/2 at transplant (35.06%\u00a0vs. 69.59%) and had lower inotrope use (22.08%\u00a0vs. 43.30%), lower IABP use (2.60%\u00a0vs. 26.29%), but higher durable CF\u2010LVAD use (19.48%\u00a0vs. 12.97%), all <jats:italic>p<\/jats:italic> &lt; 0.01. Compared to DBD\u2010donors, DCD\u2010donors used for heart\u2013kidney transplantations were younger [28(22\u201334) vs. 32(25\u201339) years, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.004]. Recipients of heart\u2013kidney transplantations from DCD\u2010donors and DBD\u2010donors had similar 6\u2010month survival using both KM analysis, and unadjusted and adjusted Cox\u2010HR models, including in propensity matched cohorts. Rates of PGF and in\u2010hospital outcomes were also similar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Use of DCD\u2010donors for multiorgan\u2010HTs has increased rapidly in the United States and early outcomes of DCD heart\u2013kidney transplantations are promising.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.15423","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T19:29:41Z","timestamp":1724354981000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Increasing Multiorgan Heart Transplantations From Donation After Circulatory Death Donors in the United States"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0613-1522","authenticated-orcid":false,"given":"Shivank","family":"Madan","sequence":"first","affiliation":[{"name":"Division of Cardiology Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill","family":"Teitelbaum","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Saeed","sequence":"additional","affiliation":[{"name":"Division of Cardiology Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vagish","family":"Hemmige","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Montefiore Medical Center  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sasha","family":"Vukelic","sequence":"additional","affiliation":[{"name":"Division of Cardiology Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yogita","family":"Rochlani","sequence":"additional","affiliation":[{"name":"Division of Cardiology Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandhya","family":"Murthy","sequence":"additional","affiliation":[{"name":"Division of Cardiology Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel B.","family":"Sims","sequence":"additional","affiliation":[{"name":"Division of Cardiology Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jooyoung","family":"Shin","sequence":"additional","affiliation":[{"name":"Division of Cardiology Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen J.","family":"Forest","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4987-051X","authenticated-orcid":false,"given":"Snehal R.","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Cardiology Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich P.","family":"Jorde","sequence":"additional","affiliation":[{"name":"Division of Cardiology Montefiore Medical Center and Albert Einstein College of Medicine  Bronx New York 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