{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:24:05Z","timestamp":1767677045612,"version":"3.41.2"},"reference-count":50,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:00:00Z","timestamp":1723075200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The study purpose was to review retrospectively our single\u2010center experience transplanting kidneys from deceased donors (DD) with acute kidney injury (AKI) according to terminal serum creatinine (tSCr) level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>AKI kidneys were defined by a doubling of the DD's admission SCr and a tSCr \u2265 2.0\u00a0mg\/dL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 1\/07 to 11\/21, we transplanted 236 AKI DD kidneys, including 100 with a tSCr \u2265 3.0\u00a0mg\/dL (high SCr AKI group, mean tSCr 4.2\u00a0mg\/dL), and the remaining 136 from DDs with a tSCr of 2.0\u20132.99\u00a0mg\/dL (lower SCr AKI group, mean tSCr 2.4\u00a0mg\/dL). These two AKI groups were compared to 996 concurrent control patients receiving DD kidneys with a tSCr &lt; 1.0\u00a0mg\/dL. Mean follow\u2010up was 69 months. Delayed graft function (DGF) rates were 51%\u00a0versus 46%\u00a0versus 29% (<jats:italic>p<\/jats:italic> &lt; 0.0001), and 5\u2010year patient and death\u2010censored kidney graft survival rates were 96.8%\u00a0versus 83.5%\u00a0versus 82.2% (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.002) and 86.7%\u00a0versus 77.8%\u00a0versus 78.8% (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.18) in the high tSCr AKI versus lower tSCr AKI versus control groups, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Despite a higher incidence of DGF, patients receiving kidneys from DDs with tSCr levels \u22653.0\u00a0mg\/dL have acceptable medium\u2010term outcomes compared to either AKI DDs with a lower tSCr or DDs with a tSCr &lt; 1.0\u00a0mg\/dL.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.15425","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T08:22:25Z","timestamp":1723105345000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Does Severity of Donor Acute Kidney Injury Influence Outcomes Following Kidney Transplantation?"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2587-653X","authenticated-orcid":false,"given":"Alexandra R.","family":"Monetti","sequence":"first","affiliation":[{"name":"Department of Surgery Wake Forest University School of Medicine  Winston\u2010Salem USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher J.","family":"Webb","sequence":"additional","affiliation":[{"name":"Department of Surgery Section of Transplantation Wake Forest School of Medicine  Winston\u2010Salem North Carolina 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