{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T22:34:32Z","timestamp":1775946872175,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T00:00:00Z","timestamp":1727136000000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Lung transplantation has become increasingly utilized in patients with COVID\u201019. While several single\u2010center and UNOS database studies have been published on lung transplants (LTs) for end\u2010stage lung disease (ESLD) from Coronavirus disease 2019 (COVID\u201019), there is a lack of multi\u2010center and international data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a multicenter analysis from 11 high\u2010volume lung transplant centers in the United States and Europe. Data were collected through the Multi\u2010Institutional ECLS Registry and stratified by ESLD due to COVID\u201019 versus other etiologies. Demographics and clinical variables were compared using Chi\u2010square test and Fisher's exact test. Survival was assessed by Kaplan\u2010Meier curves and compared by log\u2010rank test with propensity score matching.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 1606 lung transplant recipients, 46 (2.9%) were transplanted for ESLD from COVID\u201019 compared to 1560 (97.1%) without a history of COVID\u201019. Among COVID\u201019 patients, 30 (65.2%) had COVID\u201019\u2010associated ARDS and 16 (34.8%) had post\u2010COVID\u201019 fibrosis. COVID\u201019 patients had higher lung allocation scores (78.0\u00a0vs. 44.4, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001), had severely limited functional status (37.0%\u00a0vs. 2.9%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001), had higher preoperative ECMO usage (65.2%\u00a0vs. 5.4%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001), and spent less time on the waitlist (32\u00a0vs. 137 days, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001). A 30\u2010day survival was comparable between COVID\u201019 and non\u2010COVID\u201019 patients before (100%\u00a0vs. 98.7%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.39) and after propensity matching (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.15).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients who received LTs due to COVID\u201019 had short\u2010term survival comparable to that of patients without COVID\u201019. Our findings support the idea that lung transplantation should be considered for select patients with ESLD due to COVID\u201019.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.15462","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T13:00:08Z","timestamp":1727182808000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Multi\u2010Center International Analysis of Lung Transplantation Outcomes in Patients With COVID\u201019"],"prefix":"10.1111","volume":"38","author":[{"given":"Mohammed Abul","family":"Kashem","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Surgery Lewis Katz School of Medicine at Temple University  Philadelphia Pennsylvania 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Raemdonck","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery University Hospitals Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6984-6352","authenticated-orcid":false,"given":"Hannah","family":"Calvelli","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Lewis Katz School of Medicine at Temple University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andres","family":"Leon Pena","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Transplant and Circulatory Support Baylor College of Medicine  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3436-6871","authenticated-orcid":false,"given":"Marcelo","family":"Salan\u2010Gomez","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Transplant and Circulatory Support Baylor College of Medicine  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huaqing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Lewis Katz School of Medicine at Temple University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Warnick","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Surgery Lewis Katz School of Medicine at Temple University  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauricio","family":"Villavicencio","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Ius","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplant and Vascular Surgery 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