{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T11:17:02Z","timestamp":1787483822514,"version":"build-2736575974"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T00:00:00Z","timestamp":1737936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Hepatic epithelioid hemangioendothelioma (HEH) is a rare indication of liver transplant with limited evidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adult recipients undergoing first\u2010time liver\u2010only transplant from 2002 to 2021 in the United States were identified using the UNOS\/OPTN database. We compared post\u2010transplant outcomes of recipients receiving liver transplant for HEH versus other diagnoses. Survival was visualized using Kaplan\u2010Meier curves and compared using log\u2010rank test and multivariable Cox regression. Propensity score matching for recipient age, sex, and MELD was performed, with baseline characteristics and survival compared between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 111 558 liver transplant recipients identified, 121 (0.1%) underwent transplant for HEH. Donors to HEH recipients were more often living donors. Recipients with HEH were younger, more likely to be female, and had lower BMI. Recipients with HEH had higher albumin, lower bilirubin, lower INR, and lower serum creatinine, as well as lower MELD scores and rates of ascites and encephalopathy. Similar post\u2010transplant survival was observed for recipients with HEH (16.6 [lower 95% CI 14.9] years) and non\u2010HEH diagnoses (13.8 [95% CI 13.6\u201313.9] years, log\u2010rank <jats:italic>p<\/jats:italic> = 0.28), even after adjusting for baseline donor and recipient characteristics (aHR 1.28 [95% CI 0.94\u20131.74], <jats:italic>p<\/jats:italic> = 0.12). The propensity score matched cohort also had similar post\u2010LT survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This national study represents the largest known report on liver transplant for HEH. The survival of recipients with HEH was similar to other etiologies, supporting the use of liver transplantation (LT) in advanced HEH.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.70087","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T15:23:31Z","timestamp":1737991411000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Outcomes of Liver Transplant for Hepatic Epithelioid Hemangioendothelioma"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7531-1653","authenticated-orcid":false,"given":"Emily L.","family":"Larson","sequence":"first","affiliation":[{"name":"Division of Transplantation Surgery Department of Surgery Johns Hopkins Hospital  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf","family":"Ciftci","sequence":"additional","affiliation":[{"name":"Division of Transplantation Surgery Department 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