{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T21:14:45Z","timestamp":1775337285795,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,13]],"date-time":"2025-04-13T00:00:00Z","timestamp":1744502400000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Despite the critical role of glomerular filtration rate (GFR) assessment in monitoring kidney transplants, the most accurate estimate remains uncertain. This study aimed to evaluate the performance of established estimated GFR (eGFR) equations in the Vietnamese population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study involving 299 Vietnamese kidney transplant recipients (KTRs) compared measured GFR (mGFR), determined using technetium\u201099m\u2010diethylenetriaminepentaacetate (<jats:sup>99m<\/jats:sup>Tc\u2010DTPA) renal dynamic scintigraphy, with five eGFR equations (Modification of Diet in Renal Disease [MDRD], Asian modified Chronic Kidney Disease Epidemiology Collaboration [CKD\u2010EPI], CKD\u2010EPI SCysC 2012, CKD\u2010EPI SCr 2021, and CKD\u2010EPI SCr\u2013SCysC 2021). The performances of the five eGFR equations were compared based on bias, P<jats:sub>30<\/jats:sub> accuracy, absolute accuracy, precision, root mean square error (RMSE), concordance correlation coefficient (CCC), and Pearson's correlation coefficient (<jats:italic>r<\/jats:italic>), along with their 95% confidence intervals (CIs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CKD\u2010EPI SCr\u2013SCysC 2021 showed the best performance. The values for median bias, P<jats:sub>30<\/jats:sub> accuracy, absolute accuracy, precision, RMSE, CCC, and <jats:italic>r<\/jats:italic> were: 2.57 [1.22; 3.55] mL\/min\/1.73 m<jats:sup>2<\/jats:sup>, 87.6% [83.3; 90.6], 10.0% [8.3; 11.7], 11.29 [9.57; 13.40] mL\/min\/1.73 m<jats:sup>2<\/jats:sup>, 11.54 [10.42; 12.92], 0.787 [0.737; 0.828], and 0.810 [0.759; 0.850], respectively. The MDRD equation did not show significantly lower precision and accuracy than the CKD\u2010EPI SCr\u2013SCysC 2021 equation. All five equations demonstrated improved accuracy in the mGFR\u00a0\u2265 60\u00a0mL\/min\/1.73 m<jats:sup>2<\/jats:sup> subgroup compared to the mGFR &lt; 60\u00a0mL\/min\/1.73 m<jats:sup>2<\/jats:sup> subgroup.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CKD\u2010EPI SCr\u2013SCysC 2021 is the most accurate eGFR equation for Vietnamese KTRs. Further studies with larger cohorts and comparisons with gold\u2010standard methods are needed to confirm these findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.70145","type":"journal-article","created":{"date-parts":[[2025,4,13]],"date-time":"2025-04-13T17:40:31Z","timestamp":1744566031000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Performance of Five Estimated Glomerular Filtration Rate Equations in Vietnamese Kidney Transplant Recipients: A Cross\u2010Sectional Study"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3884-4156","authenticated-orcid":false,"given":"Tam Thai Thanh","family":"Tran","sequence":"first","affiliation":[{"name":"Department of Physiology Faculty of Medicine Can Tho University of Medicine and Pharmacy, An Khanh Ward, Ninh Kieu District  Can Tho City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0917-1805","authenticated-orcid":false,"given":"Tho Kieu Anh","family":"Pham","sequence":"additional","affiliation":[{"name":"Department of Physiology Faculty of Medicine Can Tho University of Medicine and Pharmacy, An Khanh Ward, Ninh Kieu District  Can Tho City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1490-0291","authenticated-orcid":false,"given":"Nghia Nhu","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Faculty of Medicine Can Tho University of Medicine and Pharmacy, An Khanh Ward, Ninh Kieu District  Can Tho City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9109-538X","authenticated-orcid":false,"given":"Thao Minh","family":"Truong","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Can Tho University of Medicine and Pharmacy, An Khanh Ward, Ninh Kieu District  Can Tho City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9340-5088","authenticated-orcid":false,"given":"Hoang Nguyen Huy","family":"Ho","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Can Tho University of Medicine and Pharmacy, An Khanh Ward, Ninh Kieu District  Can Tho City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2685-0393","authenticated-orcid":false,"given":"Chuan Khac","family":"Hoang","sequence":"additional","affiliation":[{"name":"Department of Urology Cho Ray Hospital  Ho Chi Minh City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5219-4753","authenticated-orcid":false,"given":"Sam Minh","family":"Thai","sequence":"additional","affiliation":[{"name":"Department of Urology Cho Ray Hospital  Ho Chi Minh City 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