{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:33:41Z","timestamp":1773282821012,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2025,5]]},"abstract":"ABSTRACT<\/jats:title>Background<\/jats:title>Coronary artery disease (CAD) poses a significant challenge for liver transplant recipients (LTRs) who face higher cardiovascular risks due to immunosuppressive therapies and metabolic changes. While extensive research has focused on CAD management in patients awaiting liver transplantation, data on the outcomes of percutaneous coronary intervention (PCI) in the post\u2010transplant population remain limited.<\/jats:p><\/jats:sec>Methods<\/jats:title>This retrospective cohort study used the National Inpatient Sample database (2016\u20132021) to evaluate PCI hospitalizations involving LTR and non\u2010transplant patients. Propensity score matching (1:3) was applied to balance the covariates between the LTRs and non\u2010transplant patients. The primary outcome was in\u2010hospital mortality.<\/jats:p><\/jats:sec>Results<\/jats:title>Among the 2\u00a0681\u00a0545 PCI hospitalizations, LTRs accounted for 0.1% (n<\/jats:italic>\u00a0=\u00a02675). LTRs were more likely to have diabetes (60.56%\u00a0vs. 41.36%) and chronic kidney disease (60.93%\u00a0vs. 21.06%) but less likely to have hyperlipidemia (58.32%\u00a0vs. 72.65%; all p<\/jats:italic>\u00a0<\u00a00.001). The crude rates of AKI (32.34%\u00a0vs. 16.07%; p<\/jats:italic>\u00a0<\u00a00.001) and blood transfusion (5.61%\u00a0vs. 2.76%; p<\/jats:italic>\u00a0=\u00a00.0001) were higher in the LTRs. After matching, the LTRs were associated with lower\u00a0odds of in\u2010hospital mortality (OR, 0.55; 95% CI, 0.30\u20131.00; p<\/jats:italic>\u00a0=\u00a00.05) and cardiogenic shock (OR, 0.46; 95% CI, 0.29\u20130.74; p<\/jats:italic>\u00a0=\u00a00.001). PCI hospitalizations among LTRs increased over time, peaking in 2019 (116.6\/100\u00a0000).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Despite higher comorbidities and complication rates, LTRs undergoing PCI exhibited lower in\u2010hospital mortality than non\u2010transplant patients, likely reflecting survivor bias, rigorous pre\u2010 and post\u2010transplant care, and specialized management. These preliminary findings highlight the need for further studies with detailed clinical data to validate the current findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ctr.70181","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T17:34:21Z","timestamp":1747330461000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Trends, Clinical Characteristics, and Outcomes of Percutaneous Coronary Intervention in Liver Transplant Recipients"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8557-9880","authenticated-orcid":false,"given":"Song Peng","family":"Ang","sequence":"first","affiliation":[{"name":"Department of Medicine Rutgers Health\/Community Medical Center Toms River New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia Ee","family":"Chia","sequence":"additional","affiliation":[{"name":"Department of Medicine Texas Tech University Health Science Center El Paso Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"Iglesias","sequence":"additional","affiliation":[{"name":"Department of Medicine Rutgers Health\/Community Medical Center Toms River New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chayakrit","family":"Krittanawong","sequence":"additional","affiliation":[{"name":"HumanX Delaware Delaware USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,15]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199503270-00010"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.17049"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23566"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-024-02163-x"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001104"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.981838"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(02)00826-7"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.2002.20902.x"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000001132"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/00033197241255167"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v26.i18.2138"},{"key":"e_1_2_13_13_1","unstructured":"HCUP National Inpatient Sample (NIS) \u201cHealthcare Cost and Utilization Project (HCUP) \u201d Agency for Healthcare Research and Quality Rockville MD 2016\u20102021) www.hcup\u2010us.ahrq.gov\/nisoverview.jsp."},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29168"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2021.06.845"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31023"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26972"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.25973"},{"issue":"3","key":"e_1_2_13_19_1","first-page":"239","article-title":"Intra\u2010Coronary Administration of Tacrolimus Improves Myocardial Perfusion and Left Ventricular Function in Patients With ST\u2010Segment Elevation Myocardial Infarction (COAT\u2010STEMI) Undergoing Primary Percutaneous Coronary Intervention","volume":"37","author":"Sung P. 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The IMPRESS\u20102\/MVD Study","volume":"1","author":"Ribichini F.","year":"2005","journal-title":"EuroIntervention"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.25055"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.70181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T15:50:51Z","timestamp":1748274651000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.70181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/ctr.70181"],"URL":"https:\/\/doi.org\/10.1111\/ctr.70181","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"2025-02-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70181"}}