{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T14:44:07Z","timestamp":1769784247139,"version":"3.49.0"},"reference-count":50,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T00:00:00Z","timestamp":1748908800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Nonuse of expanded criteria donor (ECD) kidneys from donation after cardiocirculatory death (DCD) donors remains high. The study purpose was to analyze our experience with kidney transplantation (KT) from DCD donors stratified by ECD versus non\u2010ECD (standard criteria donor [SCD]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Single center retrospective cohort study of all primary DCD KT recipients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      From April 2003 to January 2024, we performed 671 primary DCD KTs (554 from DCD\/SCDs and 117 from DCD\/ECDs). Mean donor and recipient ages were 38.3\u00a0\u00b1\u00a014.6 DCD\/SCD versus 59.4\u00a0\u00b1\u00a04.5\u00a0years DCD\/ECD and 54.0\u00a0\u00b1\u00a013.1 DCD\/SCD versus 63.0\u00a0\u00b1\u00a07.7\u00a0years DCD\/ECD, respectively (both\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). Mean Kidney Donor Profile Index (KDPI) values were 53\u00a0\u00b1\u00a023% DCD\/SCD versus 85\u00a0\u00b1\u00a09% DCD\/ECD (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). With a mean follow\u2010up of 71\u00a0months DCD\/SCD and 58\u00a0months DCD\/ECD, patient (76.2% DCD\/SCD vs. 72.6% DCD\/ECD) and graft survival (61.6% DCD\/SCD vs. 61.5% DCD\/ECD) rates were comparable. Rates of primary nonfunction\/thrombosis and delayed graft function were 3.4% for both DCD\/SCD and DCD\/ECD and 49% DCD\/SCD versus 56% DCD\/ECD, respectively (both\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0NS). The presence of DGF did not influence survival outcomes in DCD\/ECD KTs whereas inferior graft survival was noted in DCD\/SCD KTs with DGF. However, DGF did have a negative effect on renal function in all groups. DCD\/ECD KTs with or without DGF had comparable outcomes to DCD\/SCD KTs with DGF.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>DCD\/ECD KTs are associated with inferior functional but similar mid\u2010term survival outcomes compared to DCD\/SCD KTs with DGF. The presence of DGF appears to have a differential effect on survival outcomes in these two groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ctr.70203","type":"journal-article","created":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T13:43:17Z","timestamp":1748958197000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Experience With 117 Donation After Circulatory Death Expanded Criteria Donor Kidney Transplants: What Are the Limits of Acceptability?"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7327-4331","authenticated-orcid":false,"given":"David I.","family":"Harriman","sequence":"first","affiliation":[{"name":"Urology University of British Columbia  Vancouver BC Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher J.","family":"Webb","sequence":"additional","affiliation":[{"name":"Surgery, Section of Transplantation Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2552-2617","authenticated-orcid":false,"given":"Colleen L.","family":"Jay","sequence":"additional","affiliation":[{"name":"Surgery, Section of Transplantation Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Criscitiello","sequence":"additional","affiliation":[{"name":"Surgery, Section of Transplantation Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jigish","family":"Vyas","sequence":"additional","affiliation":[{"name":"Surgery, Section of Transplantation Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan C.","family":"Farney","sequence":"additional","affiliation":[{"name":"Surgery, Section of Transplantation Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6460-7974","authenticated-orcid":false,"given":"Giuseppe","family":"Orlando","sequence":"additional","affiliation":[{"name":"Surgery, Section of Transplantation Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"McCracken","sequence":"additional","affiliation":[{"name":"Surgery, Section of Transplantation Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amber","family":"Reeves\u2010Daniel","sequence":"additional","affiliation":[{"name":"Internal Medicine, Section of Nephrology Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Mena\u2010Gutierrez","sequence":"additional","affiliation":[{"name":"Internal Medicine, Section of Nephrology Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Sakhovskaya","sequence":"additional","affiliation":[{"name":"Internal Medicine, Section of Nephrology Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bobby","family":"Stratta","sequence":"additional","affiliation":[{"name":"Surgery, Section of Transplantation Atrium Health Wake Forest Baptist  Winston\u2010Salem North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7634-094X","authenticated-orcid":false,"given":"Robert 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