{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T12:48:04Z","timestamp":1769777284655,"version":"3.49.0"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T00:00:00Z","timestamp":1749168000000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100008310","name":"Lisa och Johan Gr\u00f6nbergs Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008310","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017138","name":"Health and Medical Care Committee of the Regional Executive Board, Region V\u00e4stra G\u00f6taland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017138","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Transplantation with a kidney from a living donor has superior long\u2010term patient and graft survival compared to a kidney from a deceased donor. For a kidney donor, feelings of stress may exist at different stages of the donation process. The aim of the study was to evaluate living kidney donors\u2019 perceived and measured stress levels before and after donation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective observational cohort study with longitudinal follow\u2010up, kidney donors were invited to answer three self\u2010rating questionnaires targeting stress, vital exhaustion, and depressive symptoms the day before and two and six months after kidney donation. At the same time points, blood and saliva samples of insulin, glucose, and cortisol were collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Analyses were based on data from seventy\u2010five individuals, with a mean age 46.5 (11) years, 60% women. The kidney donors scored low in self\u2010rating stress, exhaustion and depression both pre\u2010 and two and six months post\u2010donation, and no correlations were established between self\u2010reported measures and metabolic stress biomarkers. Post\u2010donation, however, a gender difference emerged, with women reporting decreased vitality scores 32.1 (9.3) and 30.7 (11.6) at two and six months versus men reporting increased scores 35.8 (6.9) and 36.9 (7.1). Six months post\u2010donation, women also reported more symptoms of depression than men, 12.2 (12.5) versus 6.4 (8.2) (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.058).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Kidney donors\u2019 self\u2010reported and measured stress levels and depressive symptoms were low and did not change from pre\u2010donation up to six months after donation. The low levels of subjective and objective stress reported by the donors support the limited risks associated with living kidney donation. However, six months post\u2010donation, women reported more feelings of exhaustion and depression than did men. Practitioner points: (1) The low levels of subjective and objective stress reported by kidney donors support the limited risks associated with living kidney donation. (2) Because most kidney donors are women, the gender difference in perceived stress levels presented in this study is of clinical relevance. (3) A more structured psychosocial follow\u2010up could enable the identification of individuals in need of more psychological follow\u2010up post\u2010donation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ctr.70208","type":"journal-article","created":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T04:04:30Z","timestamp":1749182670000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Kidney Donors' Perceived and Measured Stress Levels Before and After Donation, a Longitudinal Cohort Study"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2408-0087","authenticated-orcid":false,"given":"Jenny","family":"Stenberg","sequence":"first","affiliation":[{"name":"Department of Medical Sciences Renal Medicine, Uppsala University  Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9729-8701","authenticated-orcid":false,"given":"Annette","family":"Lennerling","sequence":"additional","affiliation":[{"name":"The Transplant Centre Sahlgrenska University Hospital  Gothenburg Sweden"},{"name":"Institute of Health and Care Sciences University of Gothenburg  Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen","family":"Andersson","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences Renal Medicine, Uppsala University  Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7545-5585","authenticated-orcid":false,"given":"Maria K.","family":"Svensson","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences Renal Medicine, Uppsala University  Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,6]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kisu.2021.11.003"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2014530"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.11220918"},{"key":"e_1_2_11_5_1","unstructured":"Svensk Transplantationsf\u00f6rening.Svensk Transplantationsf\u00f6rening.2019. Accessed January 24 2023.https:\/\/svensktransplantationsforening.se\/statistik\/."},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.03.034"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.12141019"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002073"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20100012.2004.00304.x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/626501"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jorc.12309"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102018\u2010026629"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13453"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13098\u2010020\u201000566\u20108"},{"key":"e_1_2_11_15_1","first-page":"67","volume-title":"The Role of Saliva Cortisol Measurement in Health and Disease","author":"Halford C.","year":"2012"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1037\/10210-010"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00149831\u2010200308000\u201000007"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167\u20105273(87)90029\u20105"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/08964280009595756"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022\u20103999(03)00610\u2010X"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044\u20108341.1959.tb00467.x"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044\u20108260.1967.tb00530.x"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1961.01710120031004"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102261\u20107\u201036"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600\u20100447.2000.102005359.x"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00280883"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472\u20106823\u201013\u201047"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.2188\/jea.JE20150183"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/tri.12974"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755\u20106686.2012.00320.x"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318153fd13"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/16.2.383"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/tri.12760"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889\u2010016\u20103352\u2010y"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfab305"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102369\u201013\u2010103"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20100012.2007.00641.x"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.70208","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ctr.70208","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.70208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T22:14:06Z","timestamp":1769724846000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.70208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/ctr.70208"],"URL":"https:\/\/doi.org\/10.1111\/ctr.70208","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2024-12-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70208"}}