{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T09:40:56Z","timestamp":1785231656318,"version":"3.55.0"},"reference-count":42,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is no consensus on the optimal perioperative management of patients undergoing kidney transplantation, and little is known about variation in clinical practice across the United States (U.S.). We conducted a national survey to describe current perioperative management practices in patients undergoing kidney transplantation in the U.S.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A survey was sent to all adult kidney transplant centers in the U.S. The survey encompassed questions on the perioperative care of kidney transplant recipients across six domains: fluid and electrolyte management, transfusion practices, hemodynamic management, neuromuscular blockade, robotic or laparoscopic\u2010assisted kidney transplants, and postoperative management and analgesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We received 68 valid responses from 55 kidney transplant centers in the U.S., representing 11\u00a0663 transplants annually (41.4% of the total national volume). There was significant heterogeneity in fluid management regarding the type and volume of fluids administered. Most centers (87.2%) targeted specific intraoperative blood pressure parameters, but there was high institutional variability in those targets. Vasopressor use was also variable; phenylephrine is used as the first\u2010line vasopressor in 26 centers (47.3%), while it is avoided by 13 centers (19.7%). Rocuronium was used by 69.1% of centers, and sugammadex reversal by 85.5%. Postoperative analgesia favored acetaminophen and IV opioids (79.6% for both agents).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This survey demonstrated significant heterogeneity in the perioperative management of kidney transplant recipients in the U.S. There is an urgent need for further research on how perioperative management strategies affect postoperative outcomes after kidney transplantation to better guide evidence\u2010based practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ctr.70395","type":"journal-article","created":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T13:15:42Z","timestamp":1764162942000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Perioperative Management of Patients Undergoing Kidney Transplantation in the United States\u2014A National Survey"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3652-0246","authenticated-orcid":false,"given":"Arun","family":"Menon","sequence":"first","affiliation":[{"name":"Department of Anesthesia and Perioperative Care University of California  San Francisco California USA"},{"name":"Department of Anaesthesia Royal Free Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Cole","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Perioperative Care University of California  San Francisco California USA"},{"name":"Department of Anaesthesia Royal Infirmary of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Perioperative Care University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8801-8365","authenticated-orcid":false,"given":"Clare","family":"Morkane","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Royal Free Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6034-6941","authenticated-orcid":false,"given":"Cara","family":"Crouch","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University of Colorado School of Medicine  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9420-0596","authenticated-orcid":false,"given":"Gebhard","family":"Wagener","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rania","family":"Elkhateb","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology University of Arkansas for Medical Sciences  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Govind","family":"Rangrass","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Critical Care SSM Health Saint Louis University Hospital  Saint Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldine","family":"Diaz","sequence":"additional","affiliation":[{"name":"Montefiore Medical Center  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0997-6272","authenticated-orcid":false,"given":"Nicholas","family":"Douville","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Critical Care Medicine Michigan Medicine  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7645-3530","authenticated-orcid":false,"given":"Dieter","family":"Adelmann","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Perioperative Care University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Global Observatory on Donation and Transplantation","author":"GODT"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajt.2025.01.020"},{"key":"e_1_2_10_4_1","volume-title":"2018 USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States","author":"United States Renal Data System","year":"2018"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2025.109397"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010020\u201005462\u2010w"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010022\u201006732\u20105"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.15461"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1308\/rcsann.2021.0365"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(23)00642\u20106"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0320082"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajt.2024.05.020"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajt.2024.06.017"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfz017"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0298051"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.51253\/pafmj.v73i2.7741"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/ija.ija_492_23"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606\u2010021\u201006737\u20101"},{"key":"e_1_2_10_19_1","volume-title":"OPTN: Search Membership"},{"key":"e_1_2_10_20_1","volume-title":"R: A Language and Environment for Statistical Computing","author":"R Core Team","year":"2021"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.19626"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfx040"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000150939.28904.81"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000419"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1258\/jrsm.2011.110180"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2012.05.042"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trre.2017.11.002"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.12914"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/frtra.2023.1215130"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2009.08.058"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.6.2260"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134\u2010002\u20101346\u2010y"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246\u2010200108000\u201000005"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/aln.0000000000005079"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0000000000000312"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/aln.0000000000005411"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/aln.0000000000003256"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.48795"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/TXD.0000000000001663"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2015.11.037"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1093\/bjs\/znac325"},{"key":"e_1_2_10_42_1","volume-title":"STRS: Scientific Registry of Transplant Recipients","author":"Program\u2010Specific Reports"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102022\u2010065320"}],"container-title":["Clinical Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.70395","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ctr.70395","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ctr.70395","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T17:35:21Z","timestamp":1772991321000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ctr.70395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,26]]},"references-count":42,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1111\/ctr.70395"],"URL":"https:\/\/doi.org\/10.1111\/ctr.70395","archive":["Portico"],"relation":{},"ISSN":["0902-0063","1399-0012"],"issn-type":[{"value":"0902-0063","type":"print"},{"value":"1399-0012","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,26]]},"assertion":[{"value":"2025-08-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70395"}}