{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:55:36Z","timestamp":1777503336509,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:00:00Z","timestamp":1765756800000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UM1TR004405"],"award-info":[{"award-number":["UM1TR004405"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Sarcopenia is a known predictor of morbidity and mortality after liver transplantation (LT); it has been assessed with computed tomography (CT) derived Psoas Area Index (PAI) and mean Hounsfield units (mHU). While literature is abundant regarding the adverse outcomes of liver transplant in sarcopenic patients, a paucity of data exists describing the change in psoas muscle area and density from pre\u2010 to post\u2010liver transplant. One hundred and four adult liver transplant recipients had pre\u2010 and post\u2010transplant CT scans analyzed with respect to PAI and mHU. Mean PAI pre\u2010transplant was 7.94 and 6.99\u00a0cm\n                    <jats:sup>2<\/jats:sup>\n                    \/m\n                    <jats:sup>2<\/jats:sup>\n                    post\u2010transplant (12% loss). Mean mHU pre\u2010transplant was 35.47 and 33.00 post\u2010transplant (7% reduction). However, stratified by pre\u2010transplant quartiles, PAI reduction was \u221215%, \u221212%, and \u22126% for the upper, mid\u2010two, and lower quartiles, respectively (\n                    <jats:italic>p<\/jats:italic>\n                    value\u00a0=\u00a00.0028). The mHU stratification was \u221215%, \u22128%, and \u00a0+\u00a012% for the upper, mid\u2010two, and lower quartiles, respectively (\n                    <jats:italic>p<\/jats:italic>\n                    value\u00a0=\u00a00.0004). No relationship was noted between PAI and mHU. PAI and mHU decreased following liver transplantation; however, the most pronounced decrease in muscle mass and density was in patients with the highest starting muscle mass and density. However, muscle mass (PAI) and composition (mHU) appear to be affected by multiple factors.\n                  <\/jats:p>","DOI":"10.1111\/ctr.70410","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T14:35:13Z","timestamp":1765809313000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Decrease in Psoas Muscle Mass and Density Following Liver Transplantation Is Greatest in Patients With the Highest Muscle Quantity and Density Pre\u2010Transplant"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1198-6610","authenticated-orcid":false,"given":"Michael G.","family":"Megaly","sequence":"first","affiliation":[{"name":"Division of Solid Organ Transplantation Department of Surgery University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5984-190X","authenticated-orcid":false,"given":"William C.","family":"Miller","sequence":"additional","affiliation":[{"name":"Division of Solid Organ Transplantation Department of Surgery University of Minnesota  Minneapolis Minnesota USA"},{"name":"University of Minnesota Medical School  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Thul","sequence":"additional","affiliation":[{"name":"MHealth Fairview University of Minnesota Medical Center  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Gullickson","sequence":"additional","affiliation":[{"name":"Division of Solid Organ Transplantation Department of Surgery University of Minnesota  Minneapolis Minnesota USA"},{"name":"University of Minnesota Medical School  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7351-7674","authenticated-orcid":false,"given":"Abraham J.","family":"Matar","sequence":"additional","affiliation":[{"name":"Division of Solid Organ Transplantation Department of Surgery University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Dryden","sequence":"additional","affiliation":[{"name":"Division of Solid Organ Transplantation Department of Surgery University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Wright","sequence":"additional","affiliation":[{"name":"Division of Solid Organ Transplantation Department of Surgery University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Mathews","sequence":"additional","affiliation":[{"name":"Division of Solid Organ Transplantation Department of Surgery University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8857-425X","authenticated-orcid":false,"given":"Jessica","family":"Fisher","sequence":"additional","affiliation":[{"name":"Division of Solid Organ Transplantation Department of Surgery University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidi","family":"Sarumi","sequence":"additional","affiliation":[{"name":"Division of Solid Organ Transplantation Department of Surgery University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Levi","family":"Teigen","sequence":"additional","affiliation":[{"name":"Department of Food Science and Nutrition University of Minnesota  St. Paul Minnesota USA"},{"name":"Division of Gastroenterology, Hepatology, and Nutrition Department of Medicine University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Lunos","sequence":"additional","affiliation":[{"name":"Biostatistical Design and Analysis Center Clinical and Translational Science Institute University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy L.","family":"Pruett","sequence":"additional","affiliation":[{"name":"Division of Solid Organ Transplantation Department of Surgery University of Minnesota  Minneapolis Minnesota 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