{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T12:55:59Z","timestamp":1782132959601,"version":"3.54.5"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pediatric heart\u2010lung transplantation (pHLTx) remains the only treatment option for children with significant and fixed elevation of pulmonary vascular resistance (PVR) in the setting of uncorrectable end\u2010stage heart disease. We aimed to determine the characteristics, waiting list course and long\u2010term outcomes for children listed for pHLTx within the Scandiatransplant region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This was a multinational, retrospective observational cohort study comprising all children &lt;18 years of age residing in Denmark, Estonia, Finland, Iceland, Norway and Sweden that were listed for pHLTx from January first 1987 until December 31\n                      <jats:sup>st<\/jats:sup>\n                      2024. Data were extracted from the Scandiatransplant registry database.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirty\u2010two children were listed for pHLTx during the study period. Seventeen (53.1%) reached transplantation with a peak in listing and transplantation during the 1990ies. Median age at listing was 12.1 years (range 1.5\u201317.6, IQR 7.6\u201315.8). No infants &lt;1 year were listed for pHLTx and there was no re\u2010listing for re\u2010transplantation during the study period. Congenital heart disease (CHD) with Eisenmenger\u00b4s syndrome was the cause of listing and transplantation in most cases (60.7% and 58.8%, respectively). Median waiting list duration was 268 days (range 3\u20133409, IQR 109\u2013822). All\u2010cause posttransplant 30\u2010day mortality was 17.6% (\n                      <jats:italic>n<\/jats:italic>\n                      = 3). Kaplan\u2013Meier estimated survival was 76.5% at 1 year, 35.3% at 5 years and 23.5% at 10 years posttransplant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Low numbers of pHLTx has been performed in Scandinavia. Long\u2010term outcomes were unfavorable, but comparable to other larger international and North American registries. The declining number of performed pHLTx may result from a combination of poor prognosis, declining incidence of Eisenmenger\u00b4s syndrome, improved surgical techniques for cardiac repair combined with lung transplantation, and increasing use of lung transplantation for isolated pulmonary vascular disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ctr.70570","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T07:31:29Z","timestamp":1779262289000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Nordic Experience of Pediatric Heart\u2010Lung Transplantation"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4726-0697","authenticated-orcid":false,"given":"Oscar","family":"van der Have","sequence":"first","affiliation":[{"name":"The Pediatric Heart Center Sk\u00e5ne University Hospital  Lund Sweden"},{"name":"The Department of Experimental Medical Science and The Wallenberg Center for Molecular Medicine Lund University  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0852-5691","authenticated-orcid":false,"given":"Michal","family":"Odermarsky","sequence":"additional","affiliation":[{"name":"The Pediatric Heart Center Sk\u00e5ne University Hospital  Lund Sweden"},{"name":"The Department of Clinical Science Lund Lund University  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1159-3206","authenticated-orcid":false,"given":"Thomas","family":"M\u00f6ller","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology Oslo University Hospital  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6746-5281","authenticated-orcid":false,"given":"Klaus","family":"Juul","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine Copenhagen University Hospital, Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1815-7327","authenticated-orcid":false,"given":"Timo","family":"Jahnukainen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology and Transplantation, Pediatric Research Center New Chidren\u2019s Hospital, Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3571-1168","authenticated-orcid":false,"given":"Ilse Duus","family":"Weinreich","sequence":"additional","affiliation":[{"name":"Scandiatransplant Aarhus University Hospital  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2590-3279","authenticated-orcid":false,"given":"Taisto","family":"Sarkola","sequence":"additional","affiliation":[{"name":"Minerva Foundation Institute for Medical Research New Children's Hospital, Helsinki University Hospital and University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5350-1472","authenticated-orcid":false,"given":"Anu K.","family":"Kaskinen","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology and Transplantation, Pediatric Research Center New Chidren\u2019s Hospital, Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5973-2618","authenticated-orcid":false,"given":"Karin","family":"Tran\u2010Lundmark","sequence":"additional","affiliation":[{"name":"The Pediatric Heart Center Sk\u00e5ne University Hospital  Lund Sweden"},{"name":"The Department of Experimental Medical Science and The Wallenberg Center for Molecular Medicine Lund University  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4753-3811","authenticated-orcid":false,"given":"H\u00e5kan","family":"W\u00e5hlander","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Gothenburg, The Pediatric Heart Center, Institute of Clinical Sciences, Sahlgrenska Academy Queen Silvia Children's Hospital, Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/HHF.0000000000000086"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01345\u20102024"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.03337\u20102020"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2025.05.020"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.70154"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2014.04.021"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/petr.13682"},{"key":"e_1_2_11_9_1","first-page":"121","article-title":"Scandiatransplant: Thirty Years of Cooperation in Organ Transplantation in the Nordic Countries","author":"Madsen M.","year":"1998","journal-title":"Clinical 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