{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T19:43:27Z","timestamp":1792611807409,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Transplantation"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Effective treatment and prevention for respiratory viral infections (RVI) in solid organ transplant recipients (SOTR) are lacking; clinical differences in COVID\u201019 and non\u2010COVID\u201019 (ncRVI) post\u2010omicron are unknown. We compared severity and outcomes across SOT groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A single\u2010center retrospective study of health system RVI in adult SOTR during 2022\u20102023 was conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 520 RVI episodes in 504 patients were included: 488 had 1 episode and 16 had 2 episodes. Lung, kidney, and heart transplant recipients comprised of 40.9%, 34.3%, and 20.8% of the cohort. There were 352 episodes of COVID\u201019 RVI and 148 ncRVI. All\u2010cause and RVI\u2010related hospitalization were comparable between COVID\u201019 and ncRVI (47.7%\u00a0vs. 43.9%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.50; 32.1%\u00a0vs. 31.1%,\n                      <jats:italic>p<\/jats:italic>\n                      = 0.91 respectively). Oxygen supplementation occurred in 11.9% of COVID\u201019 RVI and 11.5% of ncRVI with a maximum requirement (median, IQR) of 4.0 (2.0\u201018.8) and 2.0 (2.0\u20103.0) liters respectively (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.005). Intensive care unit (ICU) admission occurred in 7.1% and 6.1%; non\u2010invasive ventilation (NIV) in 2.3% and 4.1%; mechanical ventilation (I&amp;V) in 4.0% and 2.0%; and inotropic\/vasopressor support in 1.7% and 1.4%, for COVID\u201019 versus nCRVI, respectively. Patients with COVID\u201019 had ongoing symptoms in 16.8%, 10.2%, and 2.6% at 30 days, 3 month, and 12 month follow up respectively, compared with 16.9%, 4.7%, and 2.0% in ncRVI. Twelve\u2010month mortality, rejection and graft dysfunction were similar between groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>COVID\u201019 and ncRVI pose significant and comparable risk to SOTR in this post\u2010omicron era, in hospitalization, oxygen requirement, and persistent symptoms. Treatment and prevention should be prioritized in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ctr.70723","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T19:14:41Z","timestamp":1792610081000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparing the Post\u2010Omicron Impact of COVID\u201019 and Non\u2010COVID\u201019 Respiratory Viral Infections in Solid Organ Transplant Recipients"],"prefix":"10.1111","volume":"40","author":[{"given":"Beatrice Z.","family":"Sim","sequence":"first","affiliation":[{"name":"Sir Peter Maccallum Department of Oncology University of Melbourne  Melbourne Australia"},{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"},{"name":"National Centre for Infections in Cancer  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie M.","family":"Steinbrink","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeleine R.","family":"Heldman","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur W.","family":"Baker","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia A.","family":"Messina","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sana","family":"Arif","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Ni","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick C. K.","family":"Tam","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela","family":"Carugati","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Mah","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Goodwin","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilan S.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica A.","family":"Slavin","sequence":"additional","affiliation":[{"name":"Sir Peter Maccallum Department of Oncology University of Melbourne  Melbourne Australia"},{"name":"National Centre for Infections in Cancer  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle K.","family":"Yong","sequence":"additional","affiliation":[{"name":"Sir Peter Maccallum Department of Oncology University of Melbourne  Melbourne Australia"},{"name":"National Centre for Infections in Cancer  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron R.","family":"Wolfe","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and International Health Duke University School of Medicine  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.16449"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010025\u201020483\u2010y"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2024.08.024"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2025.1543629"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43856\u2010025\u201001251\u20105"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2025.107946"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2024.08.018"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.70078"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2022.02.015"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2019.05.007"},{"key":"e_1_2_11_12_1","unstructured":"H. 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