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These complications can be the first and sometimes only manifestations of SARS\u2010CoV\u20102 infection and can occur early or late in the course of the disease. However, these symptoms are more prevalent in hospitalized patients with venous thromboembolism, particularly those admitted to intensive care units. Moreover, various forms of arterial and venous thrombosis, or micro\u2010 or macro\u2010vasculature embolisms, have been reported during the current pandemic. They have led to harmful consequences, such as neurological and cardiac events, nearly all resulting from the hypercoagulable state caused by this viral infection. The severe hypercoagulability observed in patients with COVID\u201019 accounts for most cases of the disease that become critical. Therefore, anticoagulants seem to be one of the most vital therapeutics for treating this potentially life\u2010threatening condition. In the current paper, we present a thorough review of the pathophysiology of COVID\u201019\u2010induced hypercoagulable state and the use of anticoagulants to treat SARS\u2010CoV\u20102 infections in different patient groups, as well as their pros and cons.<\/jats:p>","DOI":"10.1111\/cts.13569","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T07:11:10Z","timestamp":1686899470000},"page":"1510-1525","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Anticoagulant therapy in\n                    <scp>COVID<\/scp>\n                    \u201019: A narrative review"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1085-374X","authenticated-orcid":false,"given":"Zeinab","family":"Mohseni\u00a0Afshar","sequence":"first","affiliation":[{"name":"Clinical Research Development Center, Imam Reza Hospital Kermanshah University of Medical Sciences  Kermanshah Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9426-7034","authenticated-orcid":false,"given":"Ali","family":"Tavakoli\u00a0Pirzaman","sequence":"additional","affiliation":[{"name":"Student Research Committee Babol University of Medical Sciences  Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9399-3854","authenticated-orcid":false,"given":"Rezvan","family":"Hosseinzadeh","sequence":"additional","affiliation":[{"name":"Student Research Committee Babol University of Medical Sciences  Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1362-7203","authenticated-orcid":false,"given":"Arefeh","family":"Babazadeh","sequence":"additional","affiliation":[{"name":"Infectious Diseases and Tropical Medicine Research Center Health Research Institute, Babol University of Medical Sciences  Babol Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad Ali","family":"Taghizadeh\u00a0Moghadam","sequence":"additional","affiliation":[{"name":"Student Research Committee Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1403-977X","authenticated-orcid":false,"given":"Seyed Rouhollah","family":"Miri","sequence":"additional","affiliation":[{"name":"Cancer Research Center Cancer Institute of Iran, Tehran University of Medical Science  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4210-5479","authenticated-orcid":false,"given":"Terence T.","family":"Sio","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic  Phoenix Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7920-6818","authenticated-orcid":false,"given":"Mark J. 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