{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T12:15:54Z","timestamp":1791375354810,"version":"4.3.1"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ascpt.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clinical Translational Sci"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This Perspective examines Thailand's role in cell and gene therapy, focusing on regulatory development and early clinical experience. These therapies are used in Thailand for \u03b2\u2010thalassemia, or blood cancer, together with the evolving ATMP regulatory framework and the ATMP Sandbox Project. Rather than cataloguing global indications, we analyze how selected advances intersect with Thailand's health system, highlighting opportunities and constraints for its role as a regional site for ATMP research, manufacturing, and access in Southeast Asia.<\/jats:p>","DOI":"10.1111\/cts.70561","type":"journal-article","created":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T11:34:12Z","timestamp":1776166452000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Thailand's Emerging Role in the Cell and Gene Therapy Revolution: A Review of Progress and Potential"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3162-1849","authenticated-orcid":false,"given":"Vip","family":"Viprakasit","sequence":"first","affiliation":[{"name":"Siriraj Thalassemia Center Faculty of Medicine Siriraj Hospital, Mahidol University  Bangkok Thailand"},{"name":"Department of Pediatrics Faculty of Medicine Siriraj Hospital, Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1453-0582","authenticated-orcid":false,"given":"Warut","family":"Tulalamba","sequence":"additional","affiliation":[{"name":"Siriraj Thalassemia Center Faculty of Medicine Siriraj Hospital, Mahidol University  Bangkok Thailand"},{"name":"Research Department Faculty of Medicine Siriraj Hospital, Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thidarat","family":"Suksangpleng","sequence":"additional","affiliation":[{"name":"Siriraj Thalassemia Center Faculty of Medicine Siriraj Hospital, Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supachai","family":"Ekwattanakit","sequence":"additional","affiliation":[{"name":"Siriraj Thalassemia Center Faculty of Medicine Siriraj Hospital, Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-024-02368-8"},{"issue":"2","key":"e_1_2_10_3_1","first-page":"81","article-title":"Targeted Gene Therapy: Promises and Challenges in Disease Management","volume":"7","author":"Vickram A. S.","year":"2024","journal-title":"Journal of Bio\u2010X Research"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/rth2.12586"},{"issue":"2","key":"e_1_2_10_5_1","first-page":"398","article-title":"Gene Therapy Strategies Targeting Aging\u2010Related Diseases","volume":"14","author":"Yu J.","year":"2023","journal-title":"Aging and Disease"},{"key":"e_1_2_10_6_1","volume-title":"Thailand ATMP Roadmap 2025\u20132029: Accelerating Advanced Therapy Innovation and Regulatory Excellence","author":"Ministry of Public Health Thailand","year":"2025"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-025-02267-y"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1296737"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(25)00780-9"},{"key":"e_1_2_10_10_1","unstructured":"Bangkok Post \u201cNetizens Unite to Help Thai Child With Rare Disease \u201d(2025) https:\/\/www.bangkokpost.com\/thailand\/general\/2944512\/netizens\u2010unite\u2010to\u2010help\u2010thai\u2010child\u2010with\u2010rare\u2010disease."},{"key":"e_1_2_10_11_1","unstructured":"eGuangzhou \u201cGuangdong Thailand Sign 11 Cooperation Projects. eGuangzhou News [Reforgene and Nouvogenes Therapeutics CRISPR Partnership MOU] \u201d(2025) http:\/\/www.eguangzhou.gov.cn\/2025\u201007\/02\/c_1003444.htm."}],"container-title":["Clinical and Translational Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cts.70561","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/cts.70561","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cts.70561","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T04:24:55Z","timestamp":1777955095000},"score":1,"resource":{"primary":{"URL":"https:\/\/ascpt.onlinelibrary.wiley.com\/doi\/10.1111\/cts.70561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/cts.70561"],"URL":"https:\/\/doi.org\/10.1111\/cts.70561","archive":["Portico"],"relation":{},"ISSN":["1752-8054","1752-8062"],"issn-type":[{"value":"1752-8054","type":"print"},{"value":"1752-8062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-08-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70561"}}