{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T01:20:37Z","timestamp":1792718437852,"version":"4.5.0"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,11,7]],"date-time":"2012-11-07T00:00:00Z","timestamp":1352246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:p>Neutrophilic panniculitis is an infrequent entity, considered by most authors as part of the \u2018neutrophilic dermatosis\u2019 spectrum. Few cases have been reported to be related with granulocyte colony\u2010stimulating factor (G\u2010<jats:styled-content style=\"fixed-case\">CSF<\/jats:styled-content>); we report a case of neutrophilic panniculitis and Sweet's syndrome lesions related with pegfilgrastim, a long\u2010acting G\u2010<jats:styled-content style=\"fixed-case\">CSF<\/jats:styled-content>. A 77\u2010year\u2010old woman with <jats:styled-content style=\"fixed-case\">M2<\/jats:styled-content> acute myeloid leukemia was treated with chemotherapy as well as broad\u2010spectrum antibiotics and antifungal drugs because of febrile neutropenia. Ten days after a single dose of pegfilgrastim, she developed a limited number of purple plaques on the neck, left leg, both arms and several indurated and slightly mobile nodules on her forearms. Skin biopsy of a plaque showed a diffused dermal neutrophilic infiltrate with dermal edema. Biopsy of a nodule showed a lobular neutrophilic panniculitis without vasculitis. No foreign material was found in those biopsies. No organisms were detected in blood, urine or tissue cultures. She was started with prednisolone 40\u2009mg once a day, with dramatic improvement within the next 2\u2009days. This case is noteworthy for the simultaneous appearance of Sweet's syndrome and neutrophilic panniculitis and it is the first case of neutrophilic panniculitis associated with this drug, pegfilgrastim.<\/jats:p>","DOI":"10.1111\/cup.12042","type":"journal-article","created":{"date-parts":[[2012,11,7]],"date-time":"2012-11-07T08:41:33Z","timestamp":1352277693000},"page":"46-49","source":"Crossref","is-referenced-by-count":22,"title":["Sweet's syndrome with subcutaneous involvement associated with pegfilgrastim treatment: first reported case"],"prefix":"10.1111","volume":"40","author":[{"given":"Mar","family":"Llamas\u2010Velasco","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital Universitario de La Princesa  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Garc\u00eda\u2010Mart\u00edn","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitario de La Princesa  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"S\u00e1nchez\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitario de La Princesa  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Fraga","sequence":"additional","affiliation":[{"name":"Department of Pathology Hospital Universitario de La Princesa  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amaro","family":"Garc\u00eda\u2010Diez","sequence":"additional","affiliation":[{"name":"Department of Dermatology Hospital Universitario de La Princesa  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,11,7]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.03.001"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2008.06.003"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612043452613"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.1999.00465.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.08.026"},{"key":"e_1_2_4_7_1","first-page":"858","article-title":"Sweet's syndrome and Yersinia enterocolitica infection","volume":"117","author":"Escallier F","year":"1990","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.12.028"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-9740.2006.04575.x"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06007.x"},{"key":"e_1_2_4_11_1","first-page":"503","article-title":"Sweet's syndrome associated with granulocyte colony\u2010stimulating factor","volume":"8","author":"Hasegawa M","year":"1998","journal-title":"Eur J Dermatol"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2001.01969.x"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01891.x"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/15569527.2011.579929"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.12042","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.12042","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T17:43:17Z","timestamp":1700674997000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.12042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,7]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1111\/cup.12042"],"URL":"https:\/\/doi.org\/10.1111\/cup.12042","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,7]]}}}