{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T04:14:57Z","timestamp":1768536897266,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T00:00:00Z","timestamp":1360022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:p>Hypopigmented mycosis fungoides (<jats:styled-content style=\"fixed-case\">HMF<\/jats:styled-content>) is uncommon clinical variant that was commonly observed in dark\u2010skinned individuals. We described the clinical characteristics, pathological features, immunohistochemical profile and prognosis of <jats:styled-content style=\"fixed-case\">HMF<\/jats:styled-content> in Egyptian patients. During the period from January 2004 to December 2011, we were able to diagnose and follow up 27 patients with <jats:styled-content style=\"fixed-case\">HMF<\/jats:styled-content>. The study included 18 males (66.7%) and 9 females (33.3%) with a mean age of 35.39 \u00b113.13\u2009years. The duration ranged from 1 to 6\u2009years with a mean of 3.26 \u00b11.7\u2009years. The majority of patients were skin type <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> (63%) and presented with multiple (88.9%), asymptomatic (74.1%), ill\u2010defined (70.4%) and non\u2010scaly (77.8%) lesions distributed on the trunk (81.5%). Histologically, epidermotropic lymphocytes were observed in 100%, basal alignment of lymphocytes in 81.5%, Pautrier's microabscesses in 29% and folliculotropism in 18.5%. Immunostaining showed predominance of epidermal <jats:styled-content style=\"fixed-case\">CD8<\/jats:styled-content>+ cells in 51.9% while in 29.6% <jats:styled-content style=\"fixed-case\">CD4<\/jats:styled-content>+ cells were predominant. Phototherapy was effective in 86.7% of patients with success rate 66.7% of narrow band <jats:styled-content style=\"fixed-case\">(NB)<\/jats:styled-content> ultraviolet\u2010B and 80% of psoralen ultraviolet\u2010A. <jats:styled-content style=\"fixed-case\">HMF<\/jats:styled-content> among Egyptians could be classified as non\u2010aggressive epidermotropic cytotoxic <jats:styled-content style=\"fixed-case\">CD8<\/jats:styled-content>+ variant. It is common among middle age males with skin type <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> and mostly well respond to phototherapy.<\/jats:p>","DOI":"10.1111\/cup.12093","type":"journal-article","created":{"date-parts":[[2013,1,16]],"date-time":"2013-01-16T18:46:58Z","timestamp":1358362018000},"page":"397-404","source":"Crossref","is-referenced-by-count":18,"title":["Hypopigmented mycosis fungoides in\u00a0Egyptian patients"],"prefix":"10.1111","volume":"40","author":[{"given":"Hussein M. M.","family":"Hassab\u2010El\u2010Naby","sequence":"first","affiliation":[{"name":"Department of Dermatology Faculty of Medicine, Al\u2010Azhar University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed A.","family":"El\u2010Khalawany","sequence":"additional","affiliation":[{"name":"Department of Dermatology Faculty of Medicine, Al\u2010Azhar University  Cairo Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,2,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502"},{"key":"e_1_2_6_3_1","first-page":"218","article-title":"Unusual variants of mycosis fungoides","volume":"9","author":"Abelda\u00f1o A","year":"2011","journal-title":"Skinmed"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1973.tb15444.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1985.tb05733.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1992.tb00238.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1996.tb04046.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.08.057"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(82)70026-X"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1982.tb14700.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2010.1233"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0190-9622(03)00907-1"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.77456"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.5144\/0256-4947.2012.283"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04567.x"},{"key":"e_1_2_6_16_1","first-page":"17","article-title":"Vitiligo vs. hypopigmented mycosis fungoides (histopathological and immunohistochemical study, univariate analysis)","volume":"16","author":"El\u2010Darouti MA","year":"2006","journal-title":"Eur J Dermatol"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31822e6877"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)91337-8"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(83)80011-5"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2000.017005403.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200204000-00006"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800644"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04368.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198608000-00009"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2012.00662.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2011.04197.x"},{"key":"e_1_2_6_27_1","first-page":"3287","article-title":"Hypopigmented mycosis fungoides in children: a clinicopathological study of 6 cases","volume":"90","author":"Wang T","year":"2010","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90006-9"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.12093","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.12093","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T17:32:36Z","timestamp":1700674356000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.12093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,5]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1111\/cup.12093"],"URL":"https:\/\/doi.org\/10.1111\/cup.12093","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,5]]}}}