{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T23:37:13Z","timestamp":1783640233934,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,6,27]],"date-time":"2013-06-27T00:00:00Z","timestamp":1372291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:p>Lichen planus follicularis tumidus (<jats:styled-content style=\"fixed-case\">LPFT<\/jats:styled-content>) represents an uncommon variety of lichen planus (<jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>). Clinically, it presents with prominent purplish lesions or white\u2010pigmented yellowish cysts and comedones. Histopathologically, it is similar to lichen planopilaris, and it is additionally characterized by follicles and cysts surrounded by a lichenoid lymphocytic infiltrate. The most common location is the retroauricular region, and it may be associated with other variants of <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content>. Herein, we describe the case of a 50\u2010year\u2010old woman with a history of lower limb hypertrophic <jats:styled-content style=\"fixed-case\">LP<\/jats:styled-content> who subsequently presented with multiple pink, tumid, pruritic plaques with white\u2010yellow cysts and comedones extensively affecting the bilateral face. Histopathologic examination revealed a lichenoid infiltrate surrounding the follicles and cysts. We diagnosed <jats:styled-content style=\"fixed-case\">LPFT<\/jats:styled-content> and began treatment with topical corticosteroids, antihistamines, systemic corticosteroids and oral acitretin without improvement. Subsequently, the patient had an acceptable response to cyclosporine at doses of 5\u2009mg\/kg\/day with remission of itching and tumidity but with residual cysts and comedones remaining. To date, the literature contains only 16 cases of <jats:styled-content style=\"fixed-case\">LPFT<\/jats:styled-content>. To our knowledge, this is the most severe case and is the only one with cessation of disease activity in response to cyclosporine.<\/jats:p>","DOI":"10.1111\/cup.12181","type":"journal-article","created":{"date-parts":[[2013,5,29]],"date-time":"2013-05-29T15:06:49Z","timestamp":1369840009000},"page":"818-822","source":"Crossref","is-referenced-by-count":13,"title":["Facial follicular cysts: a case of lichen planus follicularis tumidus?"],"prefix":"10.1111","volume":"40","author":[{"given":"David","family":"Jim\u00e9nez\u2010Gallo","sequence":"first","affiliation":[{"name":"Department of Dermatology Puerta del Mar University Hospital Cadiz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Albarr\u00e1n\u2010Planelles","sequence":"additional","affiliation":[{"name":"Department of Dermatology Puerta del Mar University Hospital Cadiz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Linares\u2010Barrios","sequence":"additional","affiliation":[{"name":"Department of Dermatology Puerta del Mar University Hospital Cadiz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Mart\u00ednez\u2010Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Department of Dermatology Puerta del Mar University Hospital Cadiz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Mar\u00eda","family":"B\u00e1ez\u2010Perea","sequence":"additional","affiliation":[{"name":"Department of Pathology Puerta del Mar University Hospital Cadiz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio Abraham","family":"Gonz\u00e1lez\u2010Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Dermatology Puerta del Mar University Hospital Cadiz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,27]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"147","article-title":"Lichen plan folliculaire tumidus r\u00e9tro\u2010auriculaire","volume":"104","author":"Bela\u00efch S","year":"1977","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1103641"},{"key":"e_1_2_4_4_1","first-page":"151","article-title":"Lichen plan folliculaire tumidus r\u00e9tro\u2010auriculaire bilat\u00e9ral associ\u00e9 a un lichen plan buccal banal leucok\u00e9ratosique et \u00e9rosif","volume":"104","author":"Grupper C","year":"1977","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_4_5_1","first-page":"1057","article-title":"Lichen plan folliculaire tumidus","volume":"107","author":"Baptista AP","year":"1980","journal-title":"Ann Dermatol 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