{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:47:17Z","timestamp":1759333637115},"reference-count":9,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2013,8,7]],"date-time":"2013-08-07T00:00:00Z","timestamp":1375833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:p><jats:styled-content style=\"fixed-case\">BRAF<\/jats:styled-content> inhibition therapy, used to treat melanomas with <jats:styled-content style=\"fixed-case\">BRAF<\/jats:styled-content> mutations, is associated with both neoplastic and non\u2010neoplastic cutaneous side effects including squamous cell carcinomas, warty dyskeratomas, verrucous keratoses, photosensitivity and widespread eruptions that present histopathologically as acantholytic dyskeratosis. We report a case of a patient undergoing <jats:styled-content style=\"fixed-case\">BRAF<\/jats:styled-content> inhibition therapy for disseminated melanoma with a <jats:styled-content style=\"fixed-case\">V600E<\/jats:styled-content> mutation who developed bilateral areolar leiomyomas, one of which was biopsied and the other of which resolved after discontinuation of vemurafenib therapy. To our knowledge, this is the first reported case of a mesenchymal neoplasm developing in association with <jats:styled-content style=\"fixed-case\">BRAF<\/jats:styled-content> inhibition therapy.<\/jats:p>","DOI":"10.1111\/cup.12199","type":"journal-article","created":{"date-parts":[[2013,7,27]],"date-time":"2013-07-27T01:35:24Z","timestamp":1374888924000},"page":"884-886","source":"Crossref","is-referenced-by-count":3,"title":["Bilateral areolar leiomyomas in a patient undergoing <scp>BRAF<\/scp> inhibition therapy for melanoma"],"prefix":"10.1111","volume":"40","author":[{"given":"Michael","family":"Clarke","sequence":"first","affiliation":[{"name":"Department of Pathology NorthShore University HealthSystem Evanston IL USA,"},{"name":"University of Chicago Pritzker School of Medicine Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Ortel","sequence":"additional","affiliation":[{"name":"Department of Pathology NorthShore University HealthSystem Evanston IL USA,"},{"name":"University of Chicago Pritzker School of Medicine Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce","family":"Brockstein","sequence":"additional","affiliation":[{"name":"Department of Pathology NorthShore University HealthSystem Evanston IL USA,"},{"name":"University of Chicago Pritzker School of Medicine Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theera","family":"Rojanapremsuk","sequence":"additional","affiliation":[{"name":"Department of Pathology NorthShore University HealthSystem Evanston IL USA,"},{"name":"University of Chicago Pritzker School of Medicine Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Victor","sequence":"additional","affiliation":[{"name":"Department of Pathology NorthShore University HealthSystem Evanston IL USA,"},{"name":"University of Chicago Pritzker School of Medicine Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoinette","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Pathology NorthShore University HealthSystem Evanston IL USA,"},{"name":"University of Chicago Pritzker School of Medicine Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Cibull","sequence":"additional","affiliation":[{"name":"Department of Pathology NorthShore University HealthSystem Evanston IL USA,"},{"name":"University of Chicago Pritzker School of Medicine Chicago IL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,8,7]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20073"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe1005370"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2010.03.019"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.32.4327"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.04.008"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105358"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1208958"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1339.045"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01451.x"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.12199","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.12199","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T04:48:02Z","timestamp":1696308482000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.12199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,7]]},"references-count":9,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1111\/cup.12199"],"URL":"https:\/\/doi.org\/10.1111\/cup.12199","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,7]]}}}