{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T09:46:53Z","timestamp":1777110413940,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,9,2]],"date-time":"2013-09-02T00:00:00Z","timestamp":1378080000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:p>The ingestion of large amounts of boric acid, a component of household insecticides, is a rare occurrence, characterized by a diffuse desquamative skin eruption, neutropenia, thrombocytopenia, delirium, acute renal failure and prolonged ileus. A 56\u2010year\u2010old male with a history of multiple previous suicide attempts was witnessed ingesting household roach killer and 4\u2009days later presented to the hospital with lethargy, stiffness and a diffuse erythematous and desquamative eruption with bullous formation. He subsequently developed erythema of both palms as well as alopecia totalis. Histopathology from a right arm shave biopsy revealed a mostly intact epidermis with subtle vacuolar alteration of the basal layer, scattered intraepidermal apoptotic keratinocytes, parakeratosis with alternating layers of orthokeratosis and considerable superficial exfoliation; accompanying dermal changes included vasodilatation and mild perivascular inflammation. This report describes the cutaneous and systemic complications in a rare case of boric acid ingestion. There is little published material on the symptoms and histopathology following boric acid ingestion, but knowledge of this entity is important, both to differentiate it from other causes of desquamative skin rashes and to allow the initiation of appropriate clinical care.<\/jats:p>","DOI":"10.1111\/cup.12205","type":"journal-article","created":{"date-parts":[[2013,7,29]],"date-time":"2013-07-29T13:04:46Z","timestamp":1375103086000},"page":"962-965","source":"Crossref","is-referenced-by-count":7,"title":["Boric acid ingestion clinically mimicking toxic epidermal necrolysis"],"prefix":"10.1111","volume":"40","author":[{"given":"David V.","family":"Webb","sequence":"first","affiliation":[{"name":"Department of Pathology and Dermatology University of Virginia Health System  Charlottesville VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne M.","family":"Stowman","sequence":"additional","affiliation":[{"name":"Department of Pathology and Dermatology University of Virginia Health System  Charlottesville VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James W.","family":"Patterson","sequence":"additional","affiliation":[{"name":"Department of Pathology and Dermatology University of Virginia Health System  Charlottesville VA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,2]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"113","article-title":"Chemical Disposition of Boron in Animals and Humans","volume":"102","author":"Moseman RF","year":"1994","journal-title":"Environ Health Perspect"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(82)70149-5"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1945.02860210022006"},{"key":"e_1_2_4_5_1","first-page":"1003","article-title":"Details of antiseptic surgery","volume":"2","author":"Lister J","year":"1882","journal-title":"Br Med J"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1556-4029.2007.00420.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-6757(92)90180-6"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-6757(88)90001-0"},{"key":"e_1_2_4_9_1","first-page":"1018","article-title":"Boric acid poisoning:\u2009report of 11 cases","volume":"90","author":"Wong LC","year":"1964","journal-title":"Can Med Assoc J"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2006.09.005"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-6757(86)90309-8"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)35006-4"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02783146"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(53)80304-5"},{"key":"e_1_2_4_15_1","volume-title":"Ellenhorn's medical toxicology: diagnosis and treatment of human poisoning","author":"Ellenhorn MJ","year":"1997"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650902948859"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1973.01620220057014"}],"container-title":["Journal of Cutaneous Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fcup.12205","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/cup.12205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T21:05:23Z","timestamp":1696367123000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/cup.12205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,2]]},"references-count":16,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/cup.12205"],"URL":"https:\/\/doi.org\/10.1111\/cup.12205","archive":["Portico"],"relation":{},"ISSN":["0303-6987","1600-0560"],"issn-type":[{"value":"0303-6987","type":"print"},{"value":"1600-0560","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,2]]}}}